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Updated: Jul 14, 2026

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
[Severe obstructive sleep apnea syndrome in a toddler]
Virginia León Miranda1, Angeles Sánchez Armengol, Aránzazu Ruiz García
1Unidad de Sueño, Unidad Médico-Quirúrgica de Enfermedades Respiratorias, Hospitales Universitarios Virgen del Rocío, Seville, Spain. virginia_leon@hotmail.com
Insights
Severe sleep apnea in a child resistant to initial treatments required multiple surgeries. A third adenoidectomy ultimately resolved the persistent breathing issues during sleep.
Area of Science:
- Pediatric Sleep Medicine
- Otolaryngology
- Respiratory Medicine
Background:
- Obstructive sleep apnea (OSA) in children can significantly impact growth and development.
- Adenoid hypertrophy is a common cause of pediatric OSA, often treated with adenoidectomy.
Observation:
- A 3-year-old boy presented with severe snoring, frequent awakenings, intense respiratory effort during sleep, and delayed growth since 15 months.
- Initial adenoidectomy at 18 months provided temporary relief, with symptom recurrence.
- A subsequent adenoidectomy with tonsillectomy showed no significant improvement.
Findings:
- Polysomnography confirmed severe sleep apnea-hypopnea (apnea-hypopnea index of 45).
- Continuous positive airway pressure (CPAP) improved sleep quality but did not fully resolve symptoms, particularly snoring.
- A third adenoidectomy was ultimately required to normalize the child's breathing pattern during sleep.
Implications:
- Recalcitrant pediatric sleep apnea may necessitate multiple surgical interventions.
- Persistent symptoms after initial surgeries highlight the complexity of airway obstruction.
- Complete resolution of severe sleep apnea-hypopnea was achieved through a third adenoidectomy, underscoring its potential role in refractory cases.
Abstract:
We report the case of a 3-year-old boy who had experienced intense snoring, frequent awakenings, intense respiratory effort during sleep, and delayed growth starting at the age of 15 months. He underwent adenoidectomy at 18 months. Symptoms initially improved but reappeared 3 months after surgery. He underwent a second adenoidectomy, this time with tonsillectomy, but there was no significant clinical improvement. Polysomnography revealed severe sleep apnea-hypopnea with an apnea-hypopnea index of 45. Continuous positive airway pressure improved sleep quality, although some symptoms, mainly snoring, persisted. A third adenoidectomy was necessary to normalize his breathing pattern during sleep.
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