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Updated: Jul 14, 2026

Single-cell Quantitation of mRNA and Surface Protein Expression in Simian Immunodeficiency Virus-infected CD4+ T Cells Isolated from Rhesus macaques
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Statins disrupt CCR5 and RANTES expression levels in CD4(+) T lymphocytes in vitro and preferentially decrease

Alexey A Nabatov1, Georgios Pollakis, Thomas Linnemann

  • 1Laboratory of Experimental Virology, Department of Medical Microbiology, Center of Infection and Immunity Amsterdam (CINIMA), Academic Medical Center of the University of Amsterdam, Amsterdam, The Netherlands.

Plos One
|May 24, 2007
PubMed
Summary

Statins reduce human immunodeficiency virus type 1 (HIV-1) infection by lowering CC-chemokine receptor 5 (CCR5) expression on CD4(+) lymphocytes. This effect preferentially inhibits R5 HIV-1 strains, suggesting statins

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