Related Experiment Video
Updated: Jul 14, 2026

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus (MRSA)
Published on: February 9, 2011
Acquisition of methicillin-resistant Staphylococcus aureus in the acute care setting: incidence and risk factors
Christophe Rioux1, Laurence Armand-Lefevre, Wafaa Guerinot
1Infectious Diseases Unit, Bichat-Claude Bernard Hospital, Paris, France.
Abstract:
Our objective was to assess the incidence of and risk factors for methicillin-resistant Staphylococcus aureus (MRSA) acquisition among patients in acute care wards. For 5 months, patients were screened for MRSA colonization at admission and at discharge. At admission, 6.6% of patients had cultures positive for MRSA, and 3.1% of patients who had tested negative for MRSA on admission had cultures positive for MRSA at discharge. Only the presence of chronic skin breaks at admission was independently associated with MRSA acquisition.
Insights
Methicillin-resistant Staphylococcus aureus (MRSA) can be acquired in hospitals. Chronic skin breaks at admission were the only identified risk factor for MRSA acquisition in acute care patients.
Area of Science:
- Infectious Diseases
- Epidemiology
- Hospital-Acquired Infections
Background:
- Methicillin-resistant Staphylococcus aureus (MRSA) poses a significant threat in healthcare settings.
- Understanding MRSA acquisition is crucial for infection control strategies.
Purpose of the Study:
- To determine the incidence of MRSA acquisition in acute care wards.
- To identify independent risk factors associated with MRSA acquisition.
Main Methods:
- Prospective study over 5 months.
- Screening of patients for MRSA colonization at admission and discharge.
- Statistical analysis to identify risk factors.
Main Results:
- 6.6% of patients had MRSA on admission.
- 3.1% of patients acquired MRSA during their hospital stay.
- Chronic skin breaks at admission were the sole independent predictor of MRSA acquisition.
Conclusions:
- MRSA acquisition is a concern in acute care settings.
- Targeting patients with chronic skin breaks may help prevent MRSA acquisition.
- Further research into prevention strategies is warranted.
Related Concept Videos
Clinical Significance of Antibiotic Resistance
Staphylococcal Skin Infections
Mechanism of Antibiotic Resistance in MRSA
Healthcare Associated Infections II: Preventive Measures
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies. Common...
Factors Affecting the Risk of Infection
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin create...