Related Experiment Video
Updated: Jul 14, 2026

Immunoglobulin Gene Sequence Analysis In Chronic Lymphocytic Leukemia: From Patient Material To Sequence Interpretation
Published on: November 26, 2018
[Chronic lymphocytic leukemia and loss of strength in the right arm--not a typical combination]
P Sendi1, E Puric, A Schönenberger
1Zentrum für Onkologie/Hämatologie und Transfusionsmedizin, Kantonsspital Aarau.
Abstract:
We report a case of metastatic renal cancer as a second malignancy in a patient with chronic lymphocytic leukemia (CLL). Six years after the primary CLL diagnosis, the clinical presentation of this patient was not typical for CLL, requiring further diagnostic steps. Due to the long-lasting course of CLL second cancers can occur in these patients. In addition some forms of tumors, such as Kaposi sarkoma, malignant melanoma, laryngeal carcinoma, lung cancer and Hodgkin Lymphoma are found more frequently in this patient population. Men with CLL have an increased risk for brain tumors, women for gastric and bladder cancers.
Related Concept Videos
Disorders of Leukocytes
Leukopenia may result from bone marrow disorders, autoimmune diseases, and infectious diseases. For example, conditions such as multiple myeloma and aplastic anemia can impair the bone marrow's ability to produce adequate leukocytes. Similarly, autoimmune diseases like lupus and viral infections such as HIV can prompt the immune system...
Disorders of the Skeletal Muscle
Musculoskeletal disorders
Musculoskeletal disorders involve injuries and conditions affecting the skeletal muscles and associated connective tissues. These disorders can arise from acute biomechanical stresses or chronic overuse and can occur across different age groups. Common injuries include sprains, fractures, and muscular strains, often resulting from...
Myasthenia Gravis: Overview and Treatment
These antibodies interfere with the function of the nicotinic receptors in three ways: by binding to the receptor and disrupting acetylcholine binding; by causing cross-linking of receptors which leads...
Primary Lymphoid Organs
The red bone marrow is a soft, spongy tissue nestled in the interior of long bones such as the humerus and femur. It is the site...
Myasthenia Gravis ll: Pathophysiology
Combination Therapies and Personalized Medicine
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...