Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Hepatitis01:25

Hepatitis

Hepatitis is an inflammatory condition of the liver most commonly caused by hepatotropic viruses (A–E), though non-infectious causes such as alcohol and drugs also exist.Hepatitis AHepatitis A virus (HAV) is a non-enveloped RNA virus of the Picornaviridae family. It is primarily transmitted via the fecal-oral route, typically through ingestion of contaminated food or water. After ingestion, HAV enters the bloodstream through the oropharynx or intestinal epithelium and reaches the liver. The...
Viral Hepatitis I: Introduction01:28

Viral Hepatitis I: Introduction

Viral hepatitis is an inflammatory condition of the liver caused by infection with hepatotropic viruses, most commonly hepatitis A, B, C, D, and E. Despite variations in structure and transmission, all viruses mentioned infect hepatocytes and provoke immune responses that can hinder liver function. Additionally, some non-hepatotropic viruses can also lead to hepatic inflammation.Hepatitis A VirusHepatitis A virus (HAV) is transmitted through the fecal–oral route, typically by ingestion of food...
Diseases of the Liver and Gallbladder01:26

Diseases of the Liver and Gallbladder

Liver and gallbladder diseases are a significant health concern, with prominent conditions including cirrhosis, hepatitis, non-alcoholic fatty liver disease (NAFLD), and gallstones. Jaundice is a common manifestation of liver and biliary disease.
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not related to...
Yellow Fever01:18

Yellow Fever

Yellow fever is a viral hemorrhagic disease caused by the yellow fever virus (YFV), a member of the Flaviviridae family. It is transmitted primarily by Aedes and Haemagogus mosquitoes in tropical and subtropical regions of Africa and South America. After transmission through a mosquito bite, the virus initially replicates in skin-resident immune cells such as dendritic cells and macrophages. These cells then migrate to the lymph nodes, where viral replication increases, eventually leading to...
Cirrhosis I: Introduction01:23

Cirrhosis I: Introduction

Cirrhosis is a chronic, irreversible liver disease characterized by the widespread replacement of healthy liver tissue with fibrotic scar tissue and the formation of regenerative nodules.Etiology of cirrhosisCirrhosis results from sustained liver injury that triggers progressive fibrosis and structural remodeling. The underlying causes are diverse, encompassing common and less frequent clinical conditions. Regardless of the origin, all causes lead to chronic inflammation, hepatocyte loss, and...
Pulmonary Tuberculosis V01:28

Pulmonary Tuberculosis V

Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the progression...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Facing the Challenge of Acute Autoimmune Liver Disease: Report of a Case and Review of the Literature.

Gastroenterology research·2016
Same author

DNA methylation profile of genes involved in inflammation and autoimmunity in inflammatory bowel disease.

Medicine·2014
Same author

Repair of gastric defects with an equine pericardial patch.

Surgery today·2014
Same author

DNA methylation changes in inflammatory bowel disease.

Annals of gastroenterology·2014
Same author

Surgical approach of primary splenic lymphoma: report of a case and review of the literature.

Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion·2012
Same author

Controversies and challenging therapeutic modalities in gastric cancer.

The Indian journal of surgery·2012

Related Experiment Video

Updated: Jul 14, 2026

Real-Time Polymerase Chain Reaction-Based Detection and Quantification of Hepatitis B Virus DNA
04:11

Real-Time Polymerase Chain Reaction-Based Detection and Quantification of Hepatitis B Virus DNA

Published on: December 15, 2023

Hepatitis B today.

Michael Safioleas1, Nikolaos J Lygidakis, Christine Manti

  • 12nd Department of Propedeutic Surgery, School of Medicine, Athens University, Greece. geosiam@yahoo.com

Hepato-Gastroenterology
|May 26, 2007
PubMed
Summary

Hepatitis B virus infection affects billions globally, with millions suffering chronic illness and facing risks of liver cancer. New nucleotide analogue antiviral drugs show promise for improving treatment outcomes in chronic hepatitis B patients.

Area of Science:

  • Hepatology
  • Virology
  • Public Health

Background:

  • Hepatitis B virus (HBV) infection is a significant global health concern.
  • Over 2 billion people have been infected, with more than 350 million experiencing chronic infections.
  • Chronic hepatitis B increases the risk of severe liver disease, including cirrhosis and hepatocellular carcinoma.

Purpose of the Study:

  • To highlight the global burden of Hepatitis B.
  • To discuss the challenges in managing chronic Hepatitis B.
  • To introduce the potential of new antiviral therapies.

Main Methods:

  • Review of existing literature on Hepatitis B epidemiology and treatment.
  • Analysis of the impact of chronic Hepatitis B on patient prognosis.

More Related Videos

Modeling Hepatitis B Virus Infection in Non-Hepatic 293T-NE-3NRs Cells
09:02

Modeling Hepatitis B Virus Infection in Non-Hepatic 293T-NE-3NRs Cells

Published on: June 5, 2020

"Liver-on-a-Chip" Cultures of Primary Hepatocytes and Kupffer Cells for Hepatitis B Virus Infection
10:25

"Liver-on-a-Chip" Cultures of Primary Hepatocytes and Kupffer Cells for Hepatitis B Virus Infection

Published on: February 19, 2019

Related Experiment Videos

Last Updated: Jul 14, 2026

Real-Time Polymerase Chain Reaction-Based Detection and Quantification of Hepatitis B Virus DNA
04:11

Real-Time Polymerase Chain Reaction-Based Detection and Quantification of Hepatitis B Virus DNA

Published on: December 15, 2023

Modeling Hepatitis B Virus Infection in Non-Hepatic 293T-NE-3NRs Cells
09:02

Modeling Hepatitis B Virus Infection in Non-Hepatic 293T-NE-3NRs Cells

Published on: June 5, 2020

"Liver-on-a-Chip" Cultures of Primary Hepatocytes and Kupffer Cells for Hepatitis B Virus Infection
10:25

"Liver-on-a-Chip" Cultures of Primary Hepatocytes and Kupffer Cells for Hepatitis B Virus Infection

Published on: February 19, 2019

  • Evaluation of the role of nucleotide analogues in managing Hepatitis B.

    • Main Results:

    • Hepatitis B infection poses a substantial worldwide public health challenge.
    • A significant portion of infected individuals develop chronic conditions.
    • Chronic infection leads to a high risk of mortality from liver complications.

    Conclusions:

    • New antiviral drugs, specifically nucleotide analogues, represent a hopeful advancement.
    • These therapies offer improved prognosis for individuals with chronic Hepatitis B.
    • Further research and application of these drugs are crucial for managing Hepatitis B.