Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Focusing of Light in the Eye

Focusing of Light in the Eye

Light rays enter the eye through the cornea, a transparent dome-shaped tissue that is the eye's outermost layer. The cornea bends or refracts, light rays traveling to the pupil. The shape of the cornea determines how much of the light is bent and whether the image will be focused correctly on the retina at the back of the eye. Once the light has passed through both refraction layers, it converges into a single focal point onto a small area. This is where photoreceptors start transforming...

Angle Closure Glaucoma: Treatment

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...

Glaucoma: Overview

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...

Open Angle Glaucoma: Treatment

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

TFOS lifestyle: Impact of societal challenges on the ocular surface.

The ocular surface·2023

Same author

An Unexpected Incidence of Ocular Surface Neoplasia on Pterygium Surgery. A Retrospective Clinical and Histopathological Report.

Cornea·2022

Same author

TFOS: Unique challenges and unmet needs for the management of ocular surface diseases throughout the world.

The ocular surface·2021

Same author

Severe long-term progressive corneal remodeling after bilateral simultaneous prophylactic crosslinking and topography-guided surface ablation with mitomycin.

American journal of ophthalmology case reports·2021

Same author

Short-term bilateral keratoconus progression after deep anterior lamellar keratoplasty in one eye and intracorneal ring segments and corneal crosslinking in the other due to eye rubbing.

Journal of cataract and refractive surgery·2020

Same author

Isolation of a point mutation associated with altered expression of the CmeABC efflux pump in a multidrug-resistant Campylobacter jejuni population of poultry origin.

Journal of global antimicrobial resistance·2016

Search research articles

Related Experiment Video

Updated: Jul 14, 2026

Correction of Presbyopia by Monocular Bi-Aspheric Ablation Profile

Published on: September 20, 2024

Hyperopic keratoconus.

Juan Carlos Abad¹, Abraham Awad, Joseph M Kurstin

¹Laser Eye Center of Miami, FL 33145, USA. jcabad@gmail.com

Journal of Refractive Surgery (Thorofare, N.J. : 1995)

|May 26, 2007

Summary

Hyperopic keratoconus is a rare condition that can occur in patients with hyperopia. Early detection and avoidance of laser-assisted in situ keratomileusis (LASIK) are crucial to prevent corneal ectasia.

Area of Science:

Ophthalmology
Corneal Surgery
Refractive Surgery

Background:

Keratoconus is a progressive thinning of the cornea, typically associated with myopia.
Hyperopic keratoconus, a rare variant, presents unique diagnostic and management challenges.

Observation:

This report details three patients (four eyes) diagnosed with hyperopic keratoconus.
Diagnostic methods included corneal curvature topography, ultrasonic pachymetry, and rotating Scheimpflug imaging.

Findings:

One patient developed unilateral ectasia after LASIK for hyperopic ablation, despite no other risk factors, in an eye with pre-existing signs of keratoconus.
Two other hyperopic patients exhibited corneal curvature and elevation patterns consistent with keratoconus.

Related Experiment Videos

Last Updated: Jul 14, 2026

Correction of Presbyopia by Monocular Bi-Aspheric Ablation Profile

Published on: September 20, 2024

Implications:

The findings suggest that keratoconus can manifest in hyperopic individuals, albeit rarely.
Caution is advised regarding LASIK in hyperopic eyes suspected of keratoconus to mitigate the risk of post-operative corneal ectasia.