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Updated: Jul 14, 2026

In Vivo, Percutaneous, Needle Based, Optical Coherence Tomography of Renal Masses
Published on: March 30, 2015
Ultrasonography of renal masses using contrast pulse sequence imaging: a pilot study
Margot H Wink1, Jean J M C H de la Rosette, Pilar Laguna
1Department of Urology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
Contrast pulse sequence (CPS) imaging shows promise for visualizing renal mass perfusion. This pilot study found CPS effectively differentiated between malignant and benign kidney lesions based on enhancement patterns.
Area of Science:
- Medical Imaging
- Nephrology
- Radiology
Background:
- Contrast-enhanced ultrasonography for renal masses emerged in 1994.
- Advancements in microbubble contrast agent visualization techniques continue.
- This study explores contrast pulse sequence (CPS) imaging for renal masses.
Purpose of the Study:
- To evaluate the characteristics of CPS imaging for renal masses.
- To compare CPS findings with clinical and histological diagnoses.
- To assess CPS as a perfusion imaging technique.
Main Methods:
- Eighteen patients with 20 renal masses underwent CPS imaging.
- Perfusion imaging characteristics were subjectively evaluated.
- CPS findings were correlated with clinical and histological data.
Main Results:
- Nineteen masses were visualized with CPS.
- Carcinomas exhibited inhomogeneous enhancement patterns with non-enhanced necrotic areas.
- Benign cysts (simple and complex) showed no enhancement and regular shapes.
Conclusions:
- CPS imaging characteristics were linked to clinical and histological findings.
- CPS is a potentially valuable technique for assessing renal mass perfusion.
- This pilot study highlights CPS as a promising diagnostic tool.
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