[Sarcoidosis with systemic involvement: a report of two cases]

Area of Science:

• Radiology
• Internal Medicine
• Pathology

Background:

• Sarcoidosis is a multisystemic granulomatous disease with unknown etiology.
• It commonly impacts the lungs and mediastinal lymph nodes.
• Systemic involvement, including abdominal organs and the central nervous system, can occur.

Observation:

• Two cases of sarcoidosis with systemic involvement are presented.
• Case 1: Lung, spleen, mediastinal, and abdominal lymph node involvement.
• Case 2: Lung, spleen, abdominal lymph node, and central nervous system involvement.

Findings:

• Radiological manifestations of sarcoidosis vary depending on affected organs.
• Imaging findings can include lymphadenopathy, splenomegaly, and central nervous system lesions.
• Characteristic granulomatous inflammation is the underlying pathology.

Implications:

• Recognizing diverse radiological patterns is crucial for diagnosing systemic sarcoidosis.
• Early detection through imaging aids in timely management.
• Understanding the spectrum of disease presentation improves patient outcomes.