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Related Experiment Video

Updated: Jul 14, 2026

Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease
10:28

Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease

Published on: July 24, 2019

Capit timed tests quantify age-related motor decline in normal subjects.

Pedro J Garcia Ruiz1, Vicenta Sanchez Bernardos, Manuel Bartolomé

  • 1Department of Neurology, Fundación Jiménez Díaz, Madrid, Spain. pgarcia@fjd.es

Journal of the Neurological Sciences
|May 26, 2007
PubMed
Summary

Motor performance declines with age, as shown by timed tests (TT). Simple tests like the CAPIT protocol

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Area of Science:

  • Gerontology
  • Neuroscience
  • Human Motor Control

Background:

  • Motor performance slowing is a known aspect of human aging.
  • Age-related motor decline is observable in both humans and animal models.
  • The CAPIT protocol provides standardized timed tests (TT) to assess motor function.

Purpose of the Study:

  • To quantify age-related changes in motor performance using CAPIT timed tests.
  • To establish normative data for motor performance across different age groups.
  • To compare motor performance in healthy aging adults with Parkinson's disease patients.

Main Methods:

  • Studied 60 healthy adults aged 20-87.
  • Administered four CAPIT timed tests: pronation-supination, finger dexterity, movement between two points, and walking test.
  • Compared results with 30 age-similar Parkinson's disease patients.

Main Results:

  • Motor performance showed a significant inverse correlation with age across all four CAPIT timed tests in healthy subjects.
  • Specific correlations: pronation-supination (r=0.33), finger dexterity (r=0.44), movement between two points (r=0.51), and walking test (r=0.59).
  • Motor performance deterioration was linear with increasing age.

Conclusions:

  • CAPIT timed tests effectively measure and quantify age-related motor decline in healthy individuals.
  • These simple tests can serve as valuable tools in aging research.
  • Further research could explore the utility of CAPIT TT in differentiating normal aging from neurodegenerative conditions like Parkinson's disease.