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Nutrient intake of children with intractable epilepsy compared with healthy children
Stella L Volpe1, Joan I Schall, Paul R Gallagher
1Division of Biobehavioral and Health Sciences, School of Nursing, University of Pennsylvania, Philadelphia, PA 19104-6096, USA. svolpe@nursing.upenn.edu
Insights
Children with intractable epilepsy often have poor nutrient intake, impacting growth. This study found significantly lower levels of key nutrients in epileptic children compared to healthy peers, highlighting dietary concerns.
Area of Science:
- Pediatric Nutrition
- Neurology
- Clinical Dietetics
Background:
- Growth retardation is prevalent in children with epilepsy.
- Poor dietary intake is a potential contributing factor to growth issues in this population.
Purpose of the Study:
- To compare nutrient intake in children aged 1-8 years with intractable epilepsy against healthy children.
- To assess nutrient intake against established Dietary Reference Intakes.
Main Methods:
- Cross-sectional study comparing 43 children with intractable epilepsy to NHANES 2001-2002 data (N=1,718).
- Children with epilepsy were stratified into two age groups (1.0-3.9 and 4.0-8.9 years).
- Nutrient intake analysis included total energy, macronutrients, vitamins, and minerals.
Main Results:
- Children with intractable epilepsy exhibited significantly lower intakes of energy, protein, carbohydrates, fat, fiber, and multiple vitamins and minerals (P<0.05).
- Over 30% of epileptic children had inadequate intake of vitamins D, E, K, folate, calcium, and essential fatty acids.
Conclusions:
- Children with intractable epilepsy demonstrate a pattern of decreased nutrient intake across a wide spectrum of essential nutrients.
- Healthcare professionals should educate families on adequate nutrition and consider supplementation for children with intractable epilepsy.
Abstract:
Growth retardation is common among children with epilepsy, and poor dietary intake may be one of the causes. The goal of this cross-sectional study was to compare the nutrient intake of children 1 to 8 years of age with intractable epilepsy to healthy children of the same age from the National Health and Nutrition Examination Survey 2001 to 2002 (N=1,718) and with the Dietary Reference Intakes. Children with intractable epilepsy were divided into two age groups: 1.0 to 3.9 and 4.0 to 8.9 years, to correspond with the Dietary Reference Intakes. Forty-three children with intractable epilepsy, mean age=4.7+/-2.2 years, had significantly lower intakes (P<0.05) of total energy; protein; carbohydrate; fat; dietary fiber; vitamins A, E, B-6, and B-12; riboflavin; niacin; folate; calcium; phosphorus; magnesium; zinc; copper; and selenium compared with healthy children. Thirty percent or more of the children with intractable epilepsy in both age groups had intakes below the Recommended Dietary Allowance or Adequate Intake for vitamins D, E, and K; folate; calcium; linoleic acid; and alpha-linolenic acid. Health care professionals caring for children with intractable epilepsy should be aware of this pattern of decreased nutrient intake and educate families to provide an adequate diet and/or consider vitamin/mineral supplementation.
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