Related Experiment Videos
Non-Hodgkin's lymphoma during pregnancy
M Spitzer1, M Citron, C F Ilardi
1Department of Obstetrics and Gynecology, Long Island Jewish Medical Center, Albert Einstein College of Medicine, New Hyde Park, New York 11042.
Gynecologic Oncology
|December 1, 1991
Summary
This case study shows that radiotherapy with shielding can effectively treat non-Hodgkin's lymphoma during pregnancy. The patient achieved a disease-free status 6 years post-treatment, highlighting a viable therapeutic option.
Area of Science:
- Oncology
- Maternal-Fetal Medicine
- Radiation Oncology
Background:
- Non-Hodgkin's lymphoma (NHL) is a rare complication during pregnancy.
- Management requires balancing maternal cancer treatment with fetal well-being.
Observation:
- A pregnant patient at 28 weeks gestation was diagnosed with stage IE non-Hodgkin's lymphoma.
- Treatment initiated with external radiotherapy (2635 rad) and abdominal/pelvic shielding at 30 weeks gestation.
Findings:
- The patient received radiotherapy during pregnancy and combination chemotherapy postpartum.
- A healthy baby weighing 2015g was delivered via Cesarean section at term.
- The patient remained disease-free 6 years after treatment.
Implications:
- Radiotherapy with protective shielding is a feasible and effective initial treatment for NHL in pregnancy.
- Careful consideration of fetal radiation exposure and treatment timing is crucial.
- This approach offers a potential pathway to successful maternal cancer remission and favorable fetal outcomes.