Related Experiment Video

Updated: Jul 11, 2026

Transient Expression of Proteins by Hydrodynamic Gene Delivery in Mice
12:54

Transient Expression of Proteins by Hydrodynamic Gene Delivery in Mice

Published on: May 5, 2014

Transient activation of transgene expression by hydrodynamics-based injection may cause rapid decrease in plasmid DNA

H Ochiai1, M Fujimuro, H Yokosawa

  • 1Faculty of Pharmaceutical Sciences, Hokkaido University, Kita-ku, Sapporo, Japan.

Gene Therapy
|May 26, 2007
PubMed

Keywords:
gene therapy deliveryDNA silencing mechanismshydrodynamic injectionplasmid expression

More Related Videos

Controllable Ion Channel Expression through Inducible Transient Transfection10:00

Controllable Ion Channel Expression through Inducible Transient Transfection

Published on: February 17, 2017

Hydrodynamic Renal Pelvis Injection for Non-viral Expression of Proteins in the Kidney08:26

Hydrodynamic Renal Pelvis Injection for Non-viral Expression of Proteins in the Kidney

Published on: January 8, 2018

Related Concept Videos

Transgenic Organisms00:53

Transgenic Organisms

Overview
DNA-only Transposons02:57

DNA-only Transposons

DNA-only transposons are called autonomous transposons since they code for the enzyme transposase that is required for the transposition mechanism. Insertion of transposons can alter gene functions in multiple ways. They can mutate the gene, alter gene expression by introducing a novel promoter or insulator sequence, introduce new splice sites, and change the mRNA transcripts produced, or remodel chromatin structure.
The donor site from where the transposon is excised is either degraded or...
Transgenic Plants02:50

Transgenic Plants

Recombinant DNA technology called transgenesis is often used to add a foreign gene or remove a detrimental gene from an organism. Such genetically modified organisms are called transgenic organisms.
The first-ever transgenic plant was a tobacco plant developed in 1983 that showed resistance against the tobacco mosaic virus. Since then, many transgenic plants have been developed and commercialized for improving the agricultural, ornamental, and horticultural value of a crop plant. Transgenic...
Transduction01:16

Transduction

Among the three main modes of HGT—transformation, conjugation, and transduction—transduction is unique in that it is mediated by bacteriophages, or bacterial viruses.Transduction occurs in two ways. Generalized transduction occurs during the lytic cycle of a bacteriophage infection. In this process, bacteriophages infect bacterial cells, replicate within them, and ultimately cause cell lysis, releasing newly assembled virions. Occasionally, random fragments of the bacterial genome are...