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Updated: Jul 14, 2026

05:28
A Chronic Immobilization Stress Protocol for Inducing Depression-Like Behavior in Mice
Published on: May 15, 2019
[Age-related changes in the exchange of hexosamine-containing biopolymers in rats under immobilization stress]
Abstract:
Daily double spinal immobilizations (for 60 minutes, at intervals of 7-8 hours) for 3 days were studied for their impact on the metabolism of hexosamine-containing biopolymers in the mucosa of the stomach and lung in male rats of different ages (kids, adults, and olds). At the same time, the highest increases in the level of hexosamine glycane, glycoprotein, and hexosamine-containing glycopeptides and a rise in the activity of the lysosomal enzymes N-acetyl-beta-D-hexosaminidase (EC 3.2.1.52) and alpha-L-fucosidase (EC 3.2.1.51) were revealed in the gastric mucosal homogenates in the growing rats.

