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Hashimoto's encephalopathy in an adolescent boy
1Department of Pediatrics, Postgraduate Institute of Medical Education and Research, Chandigarh, India. munniray1@yahoo.com
Indian Journal of Pediatrics
|May 29, 2007
Summary
Hashimoto's encephalopathy, a rare cause of acute brain dysfunction, can present with psychosis and seizures. Early treatment with thyroxine and anticonvulsants can lead to excellent outcomes.
Area of Science:
- Neurology
- Endocrinology
- Immunology
Background:
- Hashimoto's encephalopathy is an under-recognized neurological disorder.
- It can affect both children and adults, presenting with acute encephalopathy.
Observation:
- A 12.5-year-old boy experienced acute episodic psychosis, hallucinations, and seizures.
- Elevated antithyroid antibodies were detected in the patient.
Findings:
- Symptoms significantly improved with thyroxine replacement therapy and anticonvulsant medications.
- Electroencephalogram (EEG) results normalized within three months of follow-up.
Implications:
- Hashimoto's encephalopathy should be considered in unexplained encephalopathy and seizure cases.
- Prompt diagnosis and management are crucial for achieving favorable patient outcomes.
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