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Lymphosarcoma with urinary bladder infiltration in a horse.

R W Sweeney1, A N Hamir, R R Fisher

  • 1Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, New Bolton Center, Kennett Square 19348.

Journal of the American Veterinary Medical Association
|November 1, 1991
PubMed
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A nine-year-old Thoroughbred mare diagnosed with lymphosarcoma presented with urinary issues and weight loss. This aggressive cancer infiltrated multiple organs, leading to the horse's euthanasia.

Area of Science:

  • Veterinary Oncology
  • Equine Medicine
  • Pathology

Background:

  • Lymphosarcoma is a common hematopoietic neoplasm in horses.
  • Early diagnosis and treatment are crucial for managing equine cancers.

Observation:

  • A 9-year-old Thoroughbred mare exhibited pollakiuria, hematuria, and weight loss.
  • Physical exam revealed a pelvic mass; urine and peritoneal fluid showed neoplastic lymphocytes.
  • Necropsy confirmed extensive lymphosarcoma involving the bladder, reproductive tract, sublumbar muscles, and myocardium.

Findings:

  • Histologic diagnosis of lymphosarcoma was confirmed.
  • The neoplasm demonstrated aggressive infiltration across multiple organ systems.
  • Neoplastic lymphocytes were identified in urine sediment and peritoneal fluid.

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Implications:

  • This case highlights the aggressive nature of lymphosarcoma in horses.
  • Highlights the importance of thorough diagnostic workups for unexplained clinical signs in horses.
  • Underscores the challenges in treating widespread lymphosarcoma in equine patients.