Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[MR spectroscopy in brain tumors].

P Papanagiotou1, M Backens, I Q Grunwald

  • 1Klinik für Diagnostische und Interventionelle Neuroradiologie, Universitätsklinikum des Saarlandes, Homburg, Saar. panagiotis_papanagiotou@hotmail.com

Der Radiologe
|May 29, 2007
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Criteria for the use of plasmapheresesis in optic neuritis: A practice review from French expert centers.

Revue neurologique·2025
Same author

Performance comparison of a previously validated microhaplotype panel and a forensic STR panel for DNA mixture analysis.

Forensic science international. Genetics·2024
Same author

World Federation for Interventional Stroke Treatment (WIST) multispecialty training guidelines for endovascular stroke intervention: Time is brain! - Response to commentary by UKNG.

Clinical radiology·2024
Same author

[Orbital tumors].

Radiologie (Heidelberg, Germany)·2024
Same author

Lean mass sparing in resistance-trained athletes during caloric restriction: the role of resistance training volume.

European journal of applied physiology·2022
Same author

[Whiplash injury of the cervical spine].

Der Radiologe·2021
Same journal

Der Radiologe·2024
Same journal

Der Radiologe·2024
Same journal

Der Radiologe·2024
Same journal

Der Radiologe·2024
Same journal

Der Radiologe·2022
Same journal

Der Radiologe·2022
See all related articles

Magnetic resonance imaging (MRI) and spectroscopy (MRS) aid in diagnosing brain lesions. MRS analyzes metabolites like N-acetyl aspartate (NAA) and choline to identify tumor types and characteristics.

Area of Science:

  • Neuroimaging
  • Biochemistry
  • Oncology

Context:

  • Magnetic resonance imaging (MRI) provides anatomical detail of brain lesions.
  • Magnetic resonance spectroscopy (MRS) offers metabolic information for enhanced diagnosis.
  • Routine clinical application of MRS aids in characterizing intracerebral space-occupying lesions.

Purpose:

  • To elucidate the diagnostic utility of MRS in evaluating intracerebral lesions.
  • To detail the significance of key metabolites (NAA, creatine, choline, lactate, lipids) in MRS spectra.
  • To correlate specific metabolite patterns with different types of brain tumors.

Summary:

  • MRS detects changes in metabolites such as N-acetyl aspartate (NAA), creatine, choline, lactate, and lipids.
  • Decreased NAA and elevated choline levels are indicative of malignant brain tumors.

Related Experiment Videos

  • Lactate elevation suggests anaerobic glycolysis, common in tumors, while lipid peaks may signal necrosis or metastases.

    • Impact:

    • Provides a framework for interpreting MRS data in the context of brain tumors.
    • Enhances diagnostic accuracy for intracerebral lesions using non-invasive techniques.
    • Facilitates a deeper understanding of tumor metabolism and cellularity through spectroscopic analysis.