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Related Experiment Video

Updated: Jul 14, 2026

Vessel-Sparing Microsurgical Longitudinal Intussusception Vasoepididymostomy to Treat Epididymal Obstructive Azoospermia
06:28

Vessel-Sparing Microsurgical Longitudinal Intussusception Vasoepididymostomy to Treat Epididymal Obstructive Azoospermia

Published on: May 27, 2022

[Surgical sperm retrieval].

T Diemer1, I Schroeder-Printzen, W Weidner

  • 1Klinik und Poliklinik für Urologie und Kinderurologie, Universitätsklinikum Giessen und Marburg GmbH, Standort Giessen, Justus-Liebig-Universität Giessen, 35385, Giessen. Thorsten.Diemer@chiru.med.uni-giessen.de

Der Urologe. Ausg. A
|May 29, 2007
PubMed
Summary

Intracytoplasmic sperm injection (ICSI) enables men with severe infertility to father children. Surgical sperm retrieval techniques like MESA and TESE, combined with cryopreservation, offer a viable solution for multiple ICSI attempts.

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Area of Science:

  • Reproductive medicine
  • Andrology
  • Urology

Context:

  • Intracytoplasmic sperm injection (ICSI) revolutionized assisted reproductive technologies in the mid-1990s.
  • Severe spermatogenesis disorders and azoospermia previously presented insurmountable barriers to male fertility.
  • Surgical sperm retrieval provides a crucial alternative for men with obstructive or testicular azoospermia.

Purpose:

  • To review the efficacy of surgical sperm retrieval techniques for men with severe male factor infertility.
  • To highlight the role of microsurgical epididymial sperm aspiration (MESA) and testicular sperm extraction (TESE) in obtaining spermatozoa.
  • To emphasize the benefits of cryopreservation for maximizing the utility of retrieved spermatozoa for ICSI.

Summary:

  • ICSI allows men with severe spermatogenesis issues or azoospermia to achieve biological fatherhood.

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Last Updated: Jul 14, 2026

Vessel-Sparing Microsurgical Longitudinal Intussusception Vasoepididymostomy to Treat Epididymal Obstructive Azoospermia
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Vessel-Sparing Microsurgical Longitudinal Intussusception Vasoepididymostomy to Treat Epididymal Obstructive Azoospermia

Published on: May 27, 2022

Clinical Application of 24 G Cannula Needle and 3-0 Polypropylene Suture in Vas Deferens Exploration
07:21

Clinical Application of 24 G Cannula Needle and 3-0 Polypropylene Suture in Vas Deferens Exploration

Published on: February 10, 2023

Treatment of Ejaculatory Duct Obstruction by Seminal Vesiculoscopy Assisted Flow Modification
03:51

Treatment of Ejaculatory Duct Obstruction by Seminal Vesiculoscopy Assisted Flow Modification

Published on: December 8, 2023

  • Surgical sperm retrieval methods, including MESA and TESE, extract spermatozoa from the epididymis or testis.
  • Cryopreservation of retrieved sperm enables multiple ICSI cycles from a single surgical procedure, enhancing treatment efficiency.

    • Impact:

    • Expanded fertility options for men with previously untreatable infertility.
    • Improved success rates in assisted reproduction for severe male factor cases.
    • Reduced need for repeat surgical interventions through effective sperm cryopreservation.