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Synthesis of Triazole and Tetrazole-Functionalized Zr-Based Metal-Organic Frameworks Through Post-Synthetic Ligand Exchange
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Triazabicyclodecene: an effective isotope exchange catalyst in CDCl(3)

Cyrille Sabot1, Kanduluru Ananda Kumar, Cyril Antheaume

  • 1Laboratoire de Synthèse Bio-Organique, UMR 7175/LC1-CNRS, Université Louis Pasteur de Strasbourg, B.P. 60024, 67401 Illkirch cedex, France.

The Journal of Organic Chemistry
|May 29, 2007
PubMed
Summary

This study introduces a novel H/D exchange reaction for acidic substrates, enabling selective deuteration of ketones under mild conditions. This breakthrough offers a new method for chemical synthesis and isotopic labeling.

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