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Updated: Jul 6, 2026

Quantifying Yeast Chronological Life Span by Outgrowth of Aged Cells
Published on: May 6, 2009
Recent developments in yeast aging
Matt Kaeberlein1, Christopher R Burtner, Brian K Kennedy
1Department of Pathology, University of Washington, Seattle, Washington, United States of America. kaeber@u.washington.edu
Abstract:
In the last decade, research into the molecular determinants of aging has progressed rapidly and much of this progress can be attributed to studies in invertebrate eukaryotic model organisms. Of these, single-celled yeast is the least complicated and most amenable to genetic and molecular manipulations. Supporting the use of this organism for aging research, increasing evidence has accumulated that a subset of pathways influencing longevity in yeast are conserved in other eukaryotes, including mammals. Here we briefly outline aging in yeast and describe recent findings that continue to keep this "simple" eukaryote at the forefront of aging research.
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