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Related Concept Videos

Intrauterine Drug Delivery Systems01:21

Intrauterine Drug Delivery Systems

Controlled-release systems for intravaginal and intrauterine drug delivery have been developed primarily for the administration of contraceptive steroid hormones. These delivery routes circumvent first-pass hepatic metabolism, thereby enhancing bioavailability and allowing for reduced systemic dosages compared to oral administration. Such approaches contribute to improved therapeutic efficacy and patient compliance, particularly in long-term contraceptive regimens.Intravaginal Drug Delivery...
Birth Control Methods01:22

Birth Control Methods

Vasectomy is a surgical form of male sterilization that involves severing and sealing the vasa deferentia, preventing sperm from mixing with semen during ejaculation. Because a vasectomy does not impact the testes' ability to produce testosterone, hormone levels, libido, and sexual function generally remain unchanged. While vasectomy is highly effective in preventing pregnancy, with a success rate near 99.85%, rare cases of recanalization (spontaneous reconnection) can occur. Although vasectomy...
Drugs for Treatment of Constipation-Predominant IBS01:21

Drugs for Treatment of Constipation-Predominant IBS

Pharmacological therapies for IBS-C are designed to alleviate abdominal discomfort and enhance bowel function. In patients with IBS-C, fiber supplements may help soften stools and decrease straining, but may also lead to increased gas production and bloating. Osmotic laxatives like milk of magnesia are frequently used to soften stools and increase stool frequency in IBS-C patients. In addition, two drugs approved for use in severe IBS-C adult cases are linaclotide (Linzess) and lubiprostone...
Abdominal Regions and Quadrants01:19

Abdominal Regions and Quadrants

To promote clear communication, for instance, about the location of a patient's abdominal pain or a suspicious mass, anatomists and clinicians typically use imaginary lines to categorize the abdominopelvic cavity into either four quadrants or nine regions to identify organs in the cavity.
The simpler quadrants approach, which is more commonly used in medicine, subdivides the cavity with one horizontal and one vertical line that intersects at the patient's umbilicus (navel). The four quadrants...
Drugs for Treatment of Diarrhea-Predominant IBS01:17

Drugs for Treatment of Diarrhea-Predominant IBS

Diarrhea-predominant irritable bowel syndrome (IBS-D) is a subtype of IBS characterized primarily by frequent, loose, or watery stools, abdominal pain, and abdominal discomfort. Therapeutic approaches to managing IBS-D include dietary changes, stress management techniques, and pharmaceutical interventions.
Two specific drugs used in the treatment are alosetron (Lotronex) and eluxadoline (Viberzi). Alosetron, a 5-HT3 antagonist, works by slowing the movement of stools in the gut, reducing bowel...
Imaging Studies I: CT and MRI01:14

Imaging Studies I: CT and MRI

Introduction: MRI and CT scans are crucial advancements in medical imaging techniques, playing a vital role in diagnosing conditions related to the gastrointestinal (GI) system. Each scan serves distinct purposes, targets specific areas, and requires unique nursing duties.
Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...

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Establishment of a Rat Model for Intrauterine Adhesions via Dual Injury: Curettage and Infection
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Establishment of a Rat Model for Intrauterine Adhesions via Dual Injury: Curettage and Infection

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Contraindications to IUD and IUS use.

Anita L Nelson1

  • 1Harbor-UCLA Medical Center, Box 474, Torrance, CA 90509-2910, USA. anitanelsonwhc@earthlink.net

Contraception
|May 29, 2007
PubMed
Summary

Overly restrictive contraindications limit access to intrauterine devices (IUDs) and intrauterine systems (IUS). Revising contraindications based on scientific evidence can expand eligibility for this effective contraception method.

Area of Science:

  • Reproductive Health
  • Contraception
  • Gynecology

Background:

  • Intrauterine devices (IUDs) and intrauterine systems (IUS) are highly effective reversible contraception methods.
  • Current contraindications for IUD/IUS use are sometimes overly restrictive, limiting access for eligible women.
  • Scientific evidence supports a re-evaluation of existing contraindications.

Purpose of the Study:

  • To critically review and refine the contraindications for IUD/IUS use.
  • To identify conditions where the risks of IUD/IUS use outweigh the risks of pregnancy.
  • To promote evidence-based guidelines for IUD/IUS eligibility.

Main Methods:

  • Analysis of existing product labeling, specialty group guidelines, and peer-reviewed literature.
  • Application of a risk-benefit framework comparing IUD/IUS use versus pregnancy risk for various conditions.

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Introduction of Intracapsular Rotary-cut Procedures (IRCP): A Modified Hysteromyomectomy Procedures Facilitating Fertility Preservation

Published on: January 17, 2019

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Last Updated: Jul 14, 2026

Establishment of a Rat Model for Intrauterine Adhesions via Dual Injury: Curettage and Infection
11:44

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Introduction of Intracapsular Rotary-cut Procedures (IRCP): A Modified Hysteromyomectomy Procedures Facilitating Fertility Preservation
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Introduction of Intracapsular Rotary-cut Procedures (IRCP): A Modified Hysteromyomectomy Procedures Facilitating Fertility Preservation

Published on: January 17, 2019

  • Identification of conditions that represent true contraindications based on scientific evidence.
  • Main Results:

    • The list of contraindications for IUD/IUS use can be significantly reduced.
    • True contraindications include pregnancy, active uterine infection, uterine/cervical malignancy, inability to place/retain the device, unexplained abnormal bleeding, and adverse reactions.
    • Many previously listed contraindications are not supported by current scientific evidence.

    Conclusions:

    • A revised, evidence-based list of contraindications can expand access to IUDs/IUS.
    • Healthcare providers should rely on scientific evidence rather than overly restrictive guidelines.
    • Expanding access to IUDs/IUS supports informed reproductive health choices.