Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Bioequivalence Experimental Study Designs: Repeated Measures, Cross-Over, Carry-Over, and Latin Square Designs01:15

Bioequivalence Experimental Study Designs: Repeated Measures, Cross-Over, Carry-Over, and Latin Square Designs

Bioequivalence experimental study designs play a pivotal role in testing the effectiveness of various treatments. Key among these are the repeated measures, cross-over, carry-over, and Latin square designs. In the repeated measures design, each subject receives all treatments, allowing for temporal comparisons. This type of design is useful in reducing variability but requires careful planning to avoid bias.The cross-over design, an economical method, involves sequential administration of...
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches01:23

Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches

Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast, controlled...
Nursing Interventions II: Selecting and Classifying the Nursing Interventions01:29

Nursing Interventions II: Selecting and Classifying the Nursing Interventions

Creating and executing a nursing diagnosis helps nurses plan care and guide patient, family, and community interventions. They are developed based on a patient's physical evaluation and support measuring the outcomes. It is not recommended to select random interventions throughout the planning process. Instead, consider the following six essential factors when choosing interventions:
Community Based Intervention01:30

Community Based Intervention

Community-based interventions in mental health represent a paradigm shift from institution-centered care to treatments embedded within the fabric of local communities. By prioritizing inclusion and leveraging existing societal structures, this approach fosters a supportive environment conducive to addressing mental health challenges while promoting individual dignity and agency.
Foundations of Community Mental Health Programs
Central to the success of community-based interventions is the...
Randomized Experiments01:13

Randomized Experiments

The randomization process involves assigning study participants randomly to experimental or control groups based on their probability of being equally assigned. Randomization is meant to eliminate selection bias and balance known and unknown confounding factors so that the control group is similar to the treatment group as much as possible. A computer program and a random number generator can be used to assign participants to groups in a way that minimizes bias.
Simple randomization
Simple...
Blinding01:11

Blinding

Blinding is a commonly used method of not telling participants which treatment a subject is receiving. Blinding is a critical part of a randomized control trial or RCT. It reduces the bias that affects the results. In an RCT, blinding is used in the form of a placebo. A placebo effect occurs when untreated subjects falsely believe they have received the treatment and report improved symptoms. A placebo or a dummy treatment is administered to subjects to negate the bias caused by such an effect.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Consensus on Neonatal and Pediatric Interfacility Transport.

Air medical journal·2026
Same author

A survey-based exploratory study of factors influencing women's intentions to utilise pre-exposure prophylaxis in the Eastern Cape Province, South Africa: sociodemographic characteristics, HIV risk behaviours and transactional sex.

Therapeutic advances in infectious disease·2026
Same author

A narrative review of leveraging mHealth to reduce internalised stigma among men who have sex with men with human immunodeficiency virus in low- and middle-income countries.

Digital health·2026
Same author

Reduced Adherence to Antiretroviral Therapy in Pregnant Women With HIV With Intimate Partner Violence in the United States.

Open forum infectious diseases·2026
Same author

Overcoming Logistical Barriers to Conducting Collaborative Clinical Research Between a High-Income Country and a Low- and Middle-Income Country.

JCO global oncology·2026
Same author

Lymphangioma in the Neurosurgical Axis: A Review and Illustrative Case Report.

World neurosurgery·2025

Related Experiment Videos

Challenges in replicating interventions.

Stephanie G Bell1, Susan F Newcomer, Christine Bachrach

  • 1Agency for Healthcare Research and Quality, Rockville, Maryland, USA.

The Journal of Adolescent Health : Official Publication of the Society for Adolescent Medicine
|May 29, 2007
PubMed
Summary

Adapting effective youth risk behavior interventions for new settings requires careful documentation. Successful replication balances program fidelity with local cultural sensitivity for community-based implementation.

Related Experiment Videos

Area of Science:

  • Public Health
  • Intervention Science
  • Adolescent Health

Background:

  • Youth risk behavior interventions require adaptation for diverse settings.
  • Replication efforts are crucial for scaling effective public health programs.
  • Community-based, culturally sensitive program development is essential for youth interventions.

Purpose of the Study:

  • To document the process of adapting evidence-based youth risk behavior interventions for new settings.
  • To provide insights into best practices for intervention adaptation and replication.
  • To reflect on the challenges and successes of adapting interventions across different adolescent populations.

Main Methods:

  • Six studies funded by the National Institutes of Health (NIH) starting in 1999.
  • Researchers replicated existing HIV prevention interventions for youth in new communities or populations.
  • Systematic documentation of adaptation processes, critical intervention aspects, and outcome evaluations in new settings.

Main Results:

  • Identified common and unique issues encountered during intervention replication.
  • Discussed the processes and consequences of intervention adaptations.
  • Highlighted challenges in scaling successful interventions.

Conclusions:

  • Replicating effective interventions involves implementation design challenges.
  • Balancing fidelity to the original intervention with sensitivity to new populations is critical.
  • Successful adaptation requires careful consideration of local context and needs.