Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Gene Therapy00:59

Gene Therapy

27.7K
Gene therapy is a technique where a gene is inserted into a person’s cells to prevent or treat a serious disease. The added gene may be a healthy version of the gene that is mutated in the patient, or it could be a different gene that inactivates or compensates for the patient’s disease-causing gene. For example, in patients with severe combined immunodeficiency (SCID) due to a mutation in the gene for the enzyme adenosine deaminase, a functioning version of the gene can be...
27.7K
Multiple Allele Traits01:49

Multiple Allele Traits

38.2K
The Concept of Multiple Allelism
38.2K
Group Therapy01:26

Group Therapy

450
Group therapy is a sociocultural approach to psychological treatment, where individuals with shared psychological challenges come together under the guidance of a mental health professional. This therapeutic modality offers unique opportunities for individuals to connect, share, and grow within the context of a supportive group. By fostering mutual understanding and collaboration, group therapy can address a range of psychological concerns effectively, often complementing or surpassing the...
450
Multiple Regression01:25

Multiple Regression

4.0K
Multiple regression assesses a linear relationship between one response or dependent variable and two or more independent variables. It has many practical applications.
Farmers can use multiple regression to determine the crop yield based on more than one factor, such as water availability, fertilizer, soil properties, etc. Here, the crop yield is the response or dependent variable as it depends on the other independent variables. The analysis requires the construction of a scatter plot...
4.0K
Multiple Voltage Sources01:25

Multiple Voltage Sources

1.8K
Generally, a single battery is not enough to power some devices. In such cases, batteries can be combined in two ways: in series or in parallel.
In series, the positive terminal of one battery is connected to the negative terminal of another battery. Hence, the voltage of each battery is added to give the net voltage, which is increased because each battery boosts the electrons that enter it. The same current flows through each battery because they are connected in series.
Batteries are...
1.8K
Deformation of Member under Multiple Loadings01:11

Deformation of Member under Multiple Loadings

484
When a rod is made of different materials or has various cross-sections, it must be divided into parts that meet the necessary conditions for determining the deformation. These parts are each characterized by their internal force, cross-sectional area, length, and modulus of elasticity. These parameters are then used to compute the deformation of the entire rod.
In the case of a member with a variable cross-section, the strain is not constant but depends on the position. The deformation of an...
484

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Mechanistic Insights into the Role of Artificial Intelligence and Machine Learning in the Diagnosis and Management of Multiple Sclerosis.

Pathophysiology : the official journal of the International Society for Pathophysiology·2026
Same author

Is There a Unified Etiology of Hypoplastic Left Heart Syndrome? Evaluating Genetic, Structural, and Hemodynamic Models of Disease Initiation.

Pathophysiology : the official journal of the International Society for Pathophysiology·2026
Same author

Clinical Phenotypes of Obstructive Sleep Apnea: A Decade of Evidence Toward Personalized Management.

Pathophysiology : the official journal of the International Society for Pathophysiology·2026
Same author

From rodents to algorithms: The rise of virtual animals in drug development and neuroscience.

Clinical neurology and neurosurgery·2025
Same author

Neurogranin-MYH9 interaction regulates cytoskeletal remodeling in cerebral vasculature.

Fluids and barriers of the CNS·2025
Same author

Validation of Therapeutic Agent Conjugation to Polyvinyl Alcohol-Coated Medical Devices.

Journal of visualized experiments : JoVE·2024
Same journal

Glutamate-Glutamine metabolism and transport, implications in Parkinson's disease.

International review of neurobiology·2026
Same journal

Redox bioenergetics of neuronal senescence in Alzheimer's disease.

International review of neurobiology·2026
Same journal

Neurovascular coupling and energy substrate delivery in Alzheimer's disease.

International review of neurobiology·2026
Same journal

From metals to mitochondria: Linking trace elements to energy crisis in Alzheimer's disease.

International review of neurobiology·2026
Same journal

Invisible threats of microplastics induced toxicity: Oxidative and inflammatory pathways in the CNS and retina.

International review of neurobiology·2026
Same journal

Starved synapses: Gut microbiome dysbiosis and its role in Alzheimer's glucose impairment.

International review of neurobiology·2026
See all related articles

Related Experiment Video

Updated: Feb 8, 2026

Comprehensive Autopsy Program for Individuals with Multiple Sclerosis
09:41

Comprehensive Autopsy Program for Individuals with Multiple Sclerosis

Published on: July 19, 2019

12.0K

Evolving therapies for multiple sclerosis.

Elena Korniychuk1, John M Dempster, Eileen O'Connor

  • 1Department of Neurology, Louisiana State University Health Sciences Center, Shreveport, Louisiana 71103, USA.

International Review of Neurobiology
|May 29, 2007
PubMed
Summary
This summary is machine-generated.

New multiple sclerosis (MS) treatments are in clinical trials, offering hope for more effective therapies with fewer side effects. Research into MS causes drives the development of safer, targeted medications for this neurodegenerative disorder.

More Related Videos

A Protocol for the Use of Remotely-Supervised Transcranial Direct Current Stimulation tDCS in Multiple Sclerosis MS
08:18

A Protocol for the Use of Remotely-Supervised Transcranial Direct Current Stimulation tDCS in Multiple Sclerosis MS

Published on: December 26, 2015

18.1K
The Multiple Sclerosis Performance Test MSPT: An iPad-Based Disability Assessment Tool
11:35

The Multiple Sclerosis Performance Test MSPT: An iPad-Based Disability Assessment Tool

Published on: June 30, 2014

58.8K

Related Experiment Videos

Last Updated: Feb 8, 2026

Comprehensive Autopsy Program for Individuals with Multiple Sclerosis
09:41

Comprehensive Autopsy Program for Individuals with Multiple Sclerosis

Published on: July 19, 2019

12.0K
A Protocol for the Use of Remotely-Supervised Transcranial Direct Current Stimulation tDCS in Multiple Sclerosis MS
08:18

A Protocol for the Use of Remotely-Supervised Transcranial Direct Current Stimulation tDCS in Multiple Sclerosis MS

Published on: December 26, 2015

18.1K
The Multiple Sclerosis Performance Test MSPT: An iPad-Based Disability Assessment Tool
11:35

The Multiple Sclerosis Performance Test MSPT: An iPad-Based Disability Assessment Tool

Published on: June 30, 2014

58.8K

Area of Science:

  • Neuroscience
  • Immunology
  • Pharmacology

Background:

  • Multiple sclerosis (MS) is a disabling neurodegenerative disease.
  • Current immunomodulatory and immunosuppressive therapies improve but do not halt MS progression or prevent relapses.
  • Existing treatments have limitations including imperfect effectiveness, side effects, and toxicity.

Purpose of the Study:

  • To review promising experimental agents for multiple sclerosis currently in clinical trials.
  • To detail the nature, mechanisms of action, and side effects of these novel therapeutic candidates.
  • To highlight the ongoing need for more effective and safer MS treatments.

Main Methods:

  • Review of current clinical trial data for emerging MS therapies.
  • Analysis of preclinical and clinical findings on novel immunomodulatory agents.
  • Synthesis of information on the safety and efficacy profiles of experimental treatments.

Main Results:

  • Several experimental agents show promise in different phases of clinical trials.
  • Some agents have demonstrated both safety and potential efficacy in patient populations.
  • Understanding MS etiology is crucial for developing targeted therapies.

Conclusions:

  • There is a continuous need for the development of novel therapeutics for multiple sclerosis.
  • Emerging treatments in clinical trials represent a significant advancement in MS care.
  • Future research focused on MS etiology will facilitate the creation of more specific, safer, and effective treatments.