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Updated: Jul 14, 2026

Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
Published on: January 17, 2018
Functional paraganglioma of the middle mediastinum
Subroto Paul1, Shilpa H Jain, Robert P Gallegos
1Division of Thoracic Surgery, Brigham & Women's Hospital, Boston, Massachusetts 02115, USA.
Abstract:
We describe a 49-year-old woman with refractory hypertension resulting from a functional paraganglioma of the middle mediastinum. After aggressive medical antihypertensive control and reduction of catecholamine production, she underwent surgical resection requiring transection and subsequent reconstruction of the aorta on cardiopulmonary bypass and circulatory arrest. We believe that this is the first report of a functionally active paraganglioma of the mediastinum requiring resection with cardiopulmonary bypass and aortic reconstruction.
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