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Morphometry of the corpus callosum in normal aging and Alzheimer's disease
S Weis1, K Jellinger, E Wenger
1Institute of Anatomy, Medical University Lübeck, Federal Republic of Germany.
Journal of Neural Transmission. Supplementum
|January 1, 1991
Abstract:
Changes of the human corpus callosum in normal aging and Alzheimer's disease were analysed by means of morphometry. A standardized computerized evaluation program was implemented allowing objective, quantitative and reproducible data. The various parts of the corpus callosum showed a different pattern of changes in normal aging as compared to Alzheimer's disease. In conclusion, in normal aging affects mostly the front-temporal interhemispheric fiber systems, whereas in Alzheimer's disease the parietotemporal commissural fibers are altered.