Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Skin Cancer

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

A New Measurement Technique for Lumbosacral Transitional Vertebra and Anatomic Orientation of Sacrum (Perioperative Indicator for Lumbosacral Surgery).

Turkish neurosurgery·2026

Same author

Ernst von Bergmann and the First Neurotraumatology Book.

Turkish neurosurgery·2026

Same author

Predictive modeling of long-term improvement in occlusion outcomes following Woven EndoBridge treatment of cerebral aneurysms: A machine learning approach.

Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences·2025

Same author

The Contributions of Four Pioneers in the Incunabula Period of Modern Neurosurgery.

Turkish neurosurgery·2025

Same author

Emergency lumbar disc herniation surgery with spinal anesthesia during pregnancy: Clinical features and long-term outcome.

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia·2024

Same author

Prominent Neurosurgery Books of the Western World: How They Defined the Era of Modern Neurosurgery in the 19<sup>th</sup> Century.

Turkish neurosurgery·2024

Search research articles

Related Experiment Video

Updated: Jul 14, 2026

Identifying, Diagnosing, and Grading Malignant Peripheral Nerve Sheath Tumors in Genetically Engineered Mouse Models

Identifying, Diagnosing, and Grading Malignant Peripheral Nerve Sheath Tumors in Genetically Engineered Mouse Models

Published on: May 17, 2024

Melanotic schwannoma.

Uygur Er¹, Atilla Kazanci, Taner Eyriparmak

¹Ministry of Health, Diskapi Education and Research Hospital, 2nd Neurosurgery Clinic, Diskapi 06510, Ankara, Turkey. uygurer@gmail.com

Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia

|May 29, 2007

Summary

Melanotic schwannoma, a rare tumor of Schwann cell origin, can present with neurological symptoms. Complete surgical resection is recommended for this benign lesion to prevent recurrence.

More Related Videos

Primary Culture of Human Vestibular Schwannomas

Primary Culture of Human Vestibular Schwannomas

Published on: July 20, 2014

A Unified Methodological Framework for Vestibular Schwannoma Research

A Unified Methodological Framework for Vestibular Schwannoma Research

Published on: June 20, 2017

Related Experiment Videos

Last Updated: Jul 14, 2026

Identifying, Diagnosing, and Grading Malignant Peripheral Nerve Sheath Tumors in Genetically Engineered Mouse Models

Identifying, Diagnosing, and Grading Malignant Peripheral Nerve Sheath Tumors in Genetically Engineered Mouse Models

Published on: May 17, 2024

Primary Culture of Human Vestibular Schwannomas

Primary Culture of Human Vestibular Schwannomas

Published on: July 20, 2014

A Unified Methodological Framework for Vestibular Schwannoma Research

A Unified Methodological Framework for Vestibular Schwannoma Research

Published on: June 20, 2017

Area of Science:

Neurosurgery
Oncology
Pathology

Background:

Melanotic schwannomas are rare tumors originating from Schwann cells, characterized by melanin deposition.
These tumors are generally considered benign, though their clinical course can vary.
Accurate diagnosis is crucial to differentiate from malignant melanoma.

Observation:

A 54-year-old male presented with a 4-month history of right arm and leg hypoesthesia, pain, and weakness.
MRI revealed an intradural extramedullary lesion at the foramen magnum and C1.
Histopathological and immunohistochemical analysis confirmed a melanotic schwannoma.

Findings:

Total resection of the melanotic schwannoma was successfully performed.
The patient experienced no local recurrence over a 2-year follow-up period.
Melanotic schwannoma exhibits ultrastructural Schwann cell features and melanin production.

Implications:

Complete surgical resection is the recommended management for melanotic schwannoma.
Long-term follow-up is essential to monitor for any potential recurrence.
Distinguishing melanotic schwannoma from malignant melanoma is critical for appropriate patient management.