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High prevalence and undertreatment of hypercholesterolaemia in participants in a public stroke prevention programme

Bernhard Iglseder1, Titus Moroder, Wolfgang Staffen

  • 1Department of Neurology, Christian Doppler Klinik, Landeskliniken and Paracelsus Private Medical University Salzburg, Salzburg, Austria.

Clinical Drug Investigation
|May 30, 2007
PubMed

Insights

Hypercholesterolaemia is common and poorly controlled in Austrian stroke prevention program participants. Many individuals, especially those with multiple risk factors, do not meet treatment goals for cholesterol management.

Area of Science:

  • Cardiology
  • Neurology
  • Public Health

Background:

  • Established link between serum cholesterol and coronary heart disease (CHD) incidence.
  • Growing interest in the association between serum cholesterol and stroke risk.
  • Need to assess hypercholesterolaemia prevalence and control in stroke prevention settings.

Purpose of the Study:

  • To determine the prevalence of hypercholesterolaemia.
  • To evaluate the control of hypercholesterolaemia.
  • To analyze these factors in participants of a public stroke prevention program in Austria.

Main Methods:

  • Utilized data from 9274 participants in a stroke prevention program.
  • Categorized participants based on National Cholesterol Education Program-Adult Treatment Panel III (NCEP-ATP III) guidelines.
  • Assessed risk category, treatment eligibility, and treatment quality.

Main Results:

  • 47.9% had 0-1 risk factors, 26.4% had multiple risk factors, and 25.7% met secondary prevention criteria.
  • Low-density lipoprotein (LDL) cholesterol levels varied widely, with 18.6% having very high levels (>190 mg/dL).
  • Treatment goals were met by only 54.3% of those with 0-1 risk factors, 22.9% with multiple risk factors, and 6.2% with established CHD.

Conclusions:

  • Significant prevalence of hypercholesterolaemia was observed.
  • Control of hypercholesterolaemia was inadequate in the studied population.
  • Findings highlight a need for improved hypercholesterolaemia management in stroke prevention programs.
Abstract

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