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Recognizing the link between CKD and CVD in the primary care setting: accurate and early diagnosis for timely and
1Ralph H. Johnson VA Medical Center, Medical University of South Carolina, 109 Bee Street, Charleston, SC 29401, USA. Jan.Basile@med.va.gov
Insights
Chronic kidney disease (CKD) is a growing global health issue. Early diagnosis and management by primary care physicians can significantly improve outcomes for patients with CKD, reducing complications.
Area of Science:
- Nephrology
- Cardiology
- Primary Care Medicine
Background:
- Chronic kidney disease (CKD) prevalence is rising globally, often leading to end-stage renal disease (ESRD).
- Diabetes and hypertension are primary drivers of CKD, posing significant public health challenges.
- CKD is a major risk factor for cardiovascular disease, with cardiovascular complications being a leading cause of mortality in CKD patients.
Purpose of the Study:
- To outline key risk factors and comorbidities linked to CKD development and progression.
- To provide guidance for early diagnosis and effective management of CKD in primary care settings.
Main Methods:
- Review of current epidemiological data on CKD.
- Analysis of the relationship between hypertension, diabetes, CKD, and cardiovascular disease.
- Synthesis of recommendations for primary care intervention.
Main Results:
- Hypertension and diabetes are critical factors in CKD etiology and progression.
- CKD significantly elevates the risk of cardiovascular complications, often surpassing the risk of progressing to ESRD.
- Early recognition and management of CKD offer a substantial opportunity to improve patient outcomes.
Conclusions:
- Primary care physicians play a crucial role in the early detection and management of CKD.
- Timely intervention in CKD can mitigate progression and reduce the incidence of severe cardiovascular events.
- Addressing CKD risk factors like hypertension and diabetes is essential for public health.
Abstract:
Chronic kidney disease (CKD), which is becoming increasingly prevalent in the US and worldwide, eventually progresses to end-stage renal disease (ESRD), requiring renal replacement therapy. Diabetes and hypertension, the two leading causes of CKD, are themselves reaching near epidemic proportions. Hypertension can cause both the development and progression of CKD, and CKD is a significant risk factor for the development of cardiovascular disease. Indeed, CKD patients are more likely to die of cardiovascular complications than progress to ESRD. However, data indicate that early recognition and management of CKD can have a significant positive impact on disease outcome. This creates an important interventional opportunity for the primary care physician. This report describes the major risk factors and comorbidities associated with the development and progression of CKD and offers suggestions for timely diagnosis and management of CKD in the primary care setting.
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