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[Relationship between morphological and functional changes in the stomach with aging]
Nihon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics
|September 1, 1991
Summary
Gastric emptying remains constant with age in healthy individuals, despite age-related stomach changes like atrophic gastritis and reduced acid output. This study assessed stomach age versus chronological age.
Area of Science:
- Gastroenterology
- Gerontology
- Human Physiology
Background:
- Aging is associated with morphological and functional changes in the stomach.
- Understanding these changes is crucial for maintaining gastrointestinal health in older adults.
Purpose of the Study:
- To investigate the relationship between stomach aging and gastric emptying in healthy individuals.
- To compare chronological age with 'stomach age' based on morphological and functional assessments.
Main Methods:
- Assessed 92 healthy subjects for morphological changes (atrophic gastritis) and functional changes (maximal acid output).
- Evaluated gastric emptying using the acetaminophen method.
- Compared chronological age with stomach age.
Main Results:
- Atrophic gastritis increased, and maximal acid output significantly decreased with age.
- Gastric emptying remained constant across different ages in healthy subjects.
- No significant difference was found between chronological age and stomach age.
Conclusions:
- Despite age-related stomach degeneration, gastric emptying is well-preserved in healthy aging.
- Chronological and stomach age assessments indicate good health quality in the study cohort.