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Flow Cytometry Analysis of Immune Cell Subsets within the Murine Spleen, Bone Marrow, Lymph Nodes and Synovial Tissue in an Osteoarthritis Model

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[Syringomyelia and associated bone and joint diseases].

J-Y Alnot¹, R Rossarie, F Welby

¹Service de Chirurgie Orthopédique et Traumatologique, Département de Chirurgie du Membre Supérieur, Hôpital Bichat, 46, rue Henri-Huchard, 75877 Paris Cedex 18. jean-yves.alnot@bch.ap-hop-paris.fr

Revue De Chirurgie Orthopedique Et Reparatrice De L'Appareil Moteur

|May 31, 2007

Summary

Syringomyelia, a neurological condition, can cause bone and joint diseases, often misdiagnosed. Early recognition of syringomyelia is crucial for proper treatment and avoiding ineffective surgeries.

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Area of Science:

Neurology
Rheumatology
Orthopedics

Background:

Syringomyelia can manifest as bone and joint diseases.
Joint destruction, particularly in the shoulder and elbow, may present with minimal pain, suggesting a neurological origin.

Observation:

Two cases illustrate diagnostic challenges where initial diagnoses of rheumatoid polyarthritis or osteoarthritis were misleading.
The syringomyelic origin of bone and joint disease can be overlooked initially.

Findings:

Syringomyelia may be underdiagnosed in patients with atypical presentations.
Awareness of syringomyelia's prevalence aids diagnosis and identifies candidates for neurosurgical intervention.

Implications:

Early recognition of syringomyelia is vital for appropriate patient management.
Arthroplasty is generally not recommended for destroyed, dislocated syringomyelic joints.