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Related Experiment Video

Updated: Jul 14, 2026

Isolation and Identification of Waterborne Antibiotic-Resistant Bacteria and Molecular Characterization of their Antibiotic Resistance Genes

Isolation and Identification of Waterborne Antibiotic-Resistant Bacteria and Molecular Characterization of their Antibiotic Resistance Genes

Published on: March 3, 2023

Update on the antibacterial resistance crisis.

Arthur C Croft¹, Anthony V D'Antoni, Stephanie L Terzulli

¹Spine Research Institute of San Diego, Spring Valley, CA 91978, USA. drcroft@srisd.com

Medical Science Monitor : International Medical Journal of Experimental and Clinical Research

|May 31, 2007

Summary

Antibacterial drug resistance is a growing global crisis, with evolving bacteria becoming resistant to multiple drugs. This necessitates shared responsibility among healthcare, agriculture, and consumers to combat this public health threat.

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Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses

Published on: August 30, 2018

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Last Updated: Jul 14, 2026

Isolation and Identification of Waterborne Antibiotic-Resistant Bacteria and Molecular Characterization of their Antibiotic Resistance Genes

Isolation and Identification of Waterborne Antibiotic-Resistant Bacteria and Molecular Characterization of their Antibiotic Resistance Genes

Published on: March 3, 2023

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses

Published on: August 30, 2018

Area of Science:

Microbiology
Public Health
Pharmacology

Background:

The discovery of penicillin ushered in an era of effective infectious disease control.
Bacterial adaptation has led to increasing resistance against previously effective antimicrobial drugs.
Emergence of multidrug-resistant and panresistant bacterial strains poses a significant public health challenge.

Purpose of the Study:

To discuss the escalating crisis of antibacterial drug resistance.
To examine the factors contributing to the development of resistant bacterial strains.
To advocate for shared responsibility in addressing antimicrobial resistance.

Main Methods:

Review of historical trends in antibacterial drug development and efficacy.
Analysis of factors contributing to bacterial resistance.
Discussion of the roles of various stakeholders in the resistance crisis.

Main Results:

Effectiveness of antimicrobial drugs has waned due to bacterial adaptation.
Resistant bacterial infections are increasingly prevalent in both hospital-acquired and community-acquired settings.
Pharmaceutical industry's declining interest in developing new antimicrobial agents exacerbates the problem.

Conclusions:

Antibacterial drug resistance is a complex issue driven by multifaceted selective pressures.
Healthcare workers, facilities, the agriculture industry, and consumers all play a role in driving resistance.
A collaborative, shared approach is essential to combat the growing threat of antimicrobial resistance.