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[The correlation between pulse wave velocity and diabetic angiopathy]
T Takegoshi1, J Hirai, T Shimada
1Department of Internal Medicine, Fukui Prefectural Hospital.
Nihon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics
|September 1, 1991
Summary
Pulse wave velocity (PWV) is a key indicator of aortic stiffness in patients with diabetes. Higher PWV is linked to poorer outcomes and may signify diabetic angiopathy.
Area of Science:
- Cardiovascular Physiology
- Endocrinology
- Nephrology
Context:
- Diabetes mellitus is associated with accelerated vascular aging.
- Diabetic angiopathy, affecting micro- and macrovasculature, is a major complication.
- Aortic stiffness, measured by pulse wave velocity (PWV), is an emerging cardiovascular risk marker.
Purpose:
- To investigate the relationship between aortic pulse wave velocity (PWV) and diabetic angiopathy in patients with diabetes mellitus.
- To assess PWV in relation to diabetes treatment modalities and established risk factors.
Summary:
- Pulse wave velocity (PWV) was measured in 40 diabetic patients.
- PWV was significantly higher in patients on oral hypoglycemic agents compared to diet or insulin.
- PWV positively correlated with age, systolic blood pressure, and urinary albumin index, and was higher in patients with microalbuminuria.
Impact:
- PWV may serve as a reliable indicator of both micro- and macrovascular complications in diabetes.
- Findings suggest PWV complements traditional risk factors like hypertension and hyperglycemia in assessing diabetic angiopathy.
- This research highlights PWV as a potential tool for monitoring vascular health in diabetic populations.