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How can genetic tests be evaluated for clinical use? Experience of the UK Genetic Testing Network
Mark Kroese1, Ron L Zimmern, Peter Farndon
1Public Health Genetics Unit, Cambridge, UK. mark.kroese@srl.cam.ac.uk
Abstract:
The UK Department of Health supported the establishment of the UK Genetic Testing Network (UKGTN) in 2002. The UKGTN is a collaborative network of NHS molecular genetic laboratories that offer tests for human single gene germ-line disorders. Its objective is to provide high quality and equitable services for patients and their families who require genetic advice, diagnosis and management. The UKGTN has developed a 'Gene Dossier' process to evaluate genetic tests and recommend which tests will be provided by the National Health Service. This paper describes the UKGTN organisation and the 'Gene Dossier' process. A brief review of the UKGTN genetic test evaluation experience is presented.
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