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Related Concept Videos

Increased Intracranial Pressure l: Introduction01:14

Increased Intracranial Pressure l: Introduction

Intracranial hypertension is a sustained elevation of intracranial pressure (ICP) above 22 mm Hg. In supine adults, normal ICP is ~7–15 mm Hg.The rigid, nonexpandable cranium contains three components—brain tissue, blood, and cerebrospinal fluid (CSF)—that total ~1,700 mL in a typical adult: 1,400 mL brain (~80%), 150 mL blood (~10%), and 150 mL CSF (~10%). According to the Monro–Kellie doctrine, total intracranial volume is effectively fixed. When one component expands, CSF and venous blood...
Increased Intracranial Pressure ll: Pathophysiology01:29

Increased Intracranial Pressure ll: Pathophysiology

Increased intracranial pressure (ICP) refers to a potentially life-threatening rise in pressure inside the skull. This usually happens when there is a major change in the volume of brain tissue, blood, or cerebrospinal fluid (CSF) — the three components inside the skull. According to the Monro-Kellie doctrine, if the volume of one component increases, the volumes of the other components must decrease to maintain normal pressure. If this does not happen, ICP rises.The process often begins with...

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An Orthotopic Glioblastoma Mouse Model Maintaining Brain Parenchymal Physical Constraints and Suitable for Intravital Two-photon Microscopy
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[Infratentorial tumors].

I Q Grunwald1, C Veith, M Backens

  • 1Klinik für Diagnostische und Interventionelle Neuroradiologie, Universitätsklinikum des Saarlandes, Homburg.

Der Radiologe
|May 31, 2007
PubMed
Summary
This summary is machine-generated.

This article reviews common adult infratentorial tumors. It provides an overview of these brain tumors located in the posterior fossa.

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Area of Science:

  • Neuro-oncology
  • Neurosurgery
  • Neuropathology

Context:

  • Infratentorial tumors are a significant group of central nervous system neoplasms.
  • These tumors occur in the posterior fossa of the brain, below the tentorium cerebelli.
  • Adults present with a distinct spectrum of infratentorial tumors compared to pediatric populations.

Purpose:

  • To provide a comprehensive overview of the typical infratentorial tumors encountered in adult patients.
  • To discuss the epidemiology, clinical presentation, diagnostic approaches, and general management principles.
  • To serve as a foundational resource for clinicians and researchers interested in adult posterior fossa neoplasms.

Summary:

  • The article details common adult infratentorial tumor types, including meningiomas, acoustic neuromas (vestibular schwannomas), and metastatic lesions.
  • It covers key aspects such as characteristic symptoms (e.g., headache, ataxia, cranial nerve deficits), neuroimaging findings (MRI, CT), and histopathological features.
  • General treatment strategies, including surgical resection, radiation therapy, and adjuvant therapies, are outlined.

Impact:

  • Enhances understanding of adult infratentorial tumor characteristics and prevalence.
  • Aids in the accurate diagnosis and appropriate management planning for patients with posterior fossa tumors.
  • Contributes to the body of knowledge in neuro-oncology, potentially improving patient outcomes.