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Updated: Jul 14, 2026

A Murine Model of Hemodialysis Access-Related Hand Dysfunction
Published on: May 31, 2022
Displacement of the inferior vena cava as a factor limiting catheter performance in long-term hemodialysis patients
F Fabbian1, F Malacarne, G Russo
1Renal Unit, St. Anna Hospital, Ferrara, Italy. f.fabbian@ospfe.it
Insights
Autosomal dominant polycystic kidney disease patients with difficult vascular access may require specialized femoral catheter placement. Venography is crucial for identifying anatomical abnormalities and ensuring effective hemodialysis.
Area of Science:
- Nephrology
- Vascular Access Surgery
Background:
- Autosomal dominant polycystic kidney disease (ADPKD) is a common genetic disorder leading to kidney failure.
- Long-term hemodialysis necessitates reliable vascular access, often challenging in ADPKD patients.
- Arteriovenous fistula (AVF) options were exhausted in this patient with a history of access failure.
Observation:
- An acquired anatomical abnormality, specifically an enlarged right kidney displacing the inferior vena cava, obstructed standard femoral catheter placement.
- Phlebography confirmed the venous displacement, posing a significant challenge for adequate hemodialysis blood flow.
- Previous attempts with standard tunnelled femoral catheters were unsuccessful due to this anomaly.
Findings:
- Successful and efficient hemodialysis was achieved using a 53 cm long cuffed catheter placed in the left femoral vein.
- This customized approach overcame the anatomical obstruction caused by the enlarged polycystic kidney.
- Venography proved essential in diagnosing the anomaly and guiding the appropriate catheter selection and placement.
Implications:
- Venography is a mandatory pre-procedural investigation for patients with a history of vascular access failure, particularly those with suspected anatomical abnormalities.
- This case highlights the importance of individualized vascular access strategies in complex hemodialysis patients.
- Performing venography can prevent costly and ineffective interventions, optimizing patient care and resource utilization.
Abstract:
We report a case of a lady affected by autosomal dominant polycystic kidney disease who had been on hemodialyis for 24 years. She has exhausted all options for arterious-venous fistula. The presence of an acquired anatomical abnormality was an obstacle in order to get appropriate blood flow from standard tunnelled femoral catheters. The enlarged right kidney was pushing the inferior vena cava to the left side of the abdomen, and the abnormality was demonstrated by phlebography. Only after placing a cuffed catheter 53 cm long in her left femoral vein we could dialyze efficiently. Venography is mandatory before placing a cuffed catheter especially in uremic patients with long history of access failure, because it saves costs.
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