[Calibrating the SCORE cardiovascular risk chart for use in Spain].

Area of Science:

• Cardiovascular Disease Prevention
• Risk Stratification
• Public Health Interventions

Context:

• The European Task Force recommends the SCORE function for 10-year cardiovascular mortality prediction.
• Accurate risk assessment is crucial for guiding clinical interventions.
• Existing risk functions may require regional calibration.

Purpose:

• To calibrate the SCORE cardiovascular risk prediction function for the Spanish population.
• To adapt the SCORE function using Spanish epidemiological data.
• To improve the accuracy of cardiovascular risk assessment in Spain.

Summary:

• A calibrated SCORE function for Spain yielded 13% higher risk estimates compared to the low-risk algorithm.
• Differences in risk varied by age, sex, and smoking status.
• The calibrated chart identified new high-risk situations, especially in men over 55.

Impact:

• Enables more appropriate clinical and public health decisions for cardiovascular prevention in Spain.
• Highlights the need for population-specific risk calibration.
• Facilitates targeted interventions for individuals at higher cardiovascular risk.