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Updated: Jul 14, 2026

A Morphometric and Cellular Analysis Method for the Murine Mandibular Condyle
Published on: January 11, 2018
Cone beam CT and conventional tomography for the detection of morphological temporomandibular joint changes
1Department of Oral Radiology, School of Dentistry, Faculty of Health Sciences, University of Aarhus, Vennelyst Boulevard 9, DK-8000 Aarhus C, Denmark. hhintze@odont.au.dk
Objective:
To compare the diagnostic accuracy of cone beam CT images with conventional tomographic images for the detection of morphological temporomandibular joint (TMJ) changes.
Methods:
80 dry human skulls were scanned using a NewTom 3G scanner and lateral and frontal reconstructions of the right and the left TMJs were performed. In addition, lateral and frontal cross-sectional tomograms of the skulls' TMJs were obtained in a Cranex Tome unit with Digora storage phosphor plates. Naked-eye inspection of the TMJs performed by three observers served as the gold standard for the true presence of morphological changes. The mandibular fossae were excluded from the study due to few changes in this joint component. The NewTom and the conventional tomographic images were examined by three independent observers using a binary scale for the presence of morphological changes in the condyle (flattening, defects and osteophytes) and the articular tubercle (flattening and defects). The accuracy for the different types of changes in relation to the condyles and the articular tubercles was expressed as sensitivity and specificity values, whereas the diagnostic accuracy for a general assessment including all changes in both joint components was expressed by the sum of cases where the gold standard and the radiographic scores were not identical (absolute difference). Differences between the two radiographic modalities were tested by paired t-test.
Results:
Detection of the various types of morphological changes in relation to the condyle and the articular tubercle assessed separately resulted in no significant differences between the two radiographic modalities, with the exception of bone defects in the articular tubercle examined on frontal views alone where the specificity with tomography was significantly higher than with cone beam CT. Detection of all morphological changes in relation to both the condyle and the articular tubercle showed a significantly higher accuracy with tomography than with cone beam CT using lateral views alone, but there was no significant difference between the two modalities using frontal views alone and lateral and frontal views in combination.
Conclusion:
In general, no significant differences in diagnostic accuracy for the detection of bone changes in the condyle and in the articular tubercle were found between cone beam CT images and conventional tomograms.
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