Related Experiment Video

Updated: Jul 14, 2026

Catheter-based Endovascular Angioplasty for Fibrosing Mediastinitis-associated Pulmonary Vein Stenosis
06:59

Catheter-based Endovascular Angioplasty for Fibrosing Mediastinitis-associated Pulmonary Vein Stenosis

Published on: August 26, 2025

[Very late intrastent thrombosis--at 27 months!]

F Digne1, B Gérardin, R Pillière

  • 1Unlté de cardiologie interventionnelle, Clinique Ambroise Paré, 25-27 boulevard Victor Hugo, 92200 Neuilly-sur-Seine.

Archives Des Maladies Du Coeur Et Des Vaisseaux
|June 1, 2007
PubMed

Insights

Stopping antiplatelet therapy in stented heart patients increases cardiac risks. Late stent thrombosis, even with bare metal stents, can occur after surgery if therapy is interrupted.

Area of Science:

  • Cardiology
  • Vascular Surgery

Background:

  • Platelet antiaggregant therapy is crucial for patients with coronary stents to prevent complications.
  • While acute stent thrombosis is recognized, late stent thrombosis is less common, particularly with drug-eluting stents.

Observation:

  • A 54-year-old man experienced thrombosis of a bare metal stent implanted 27 months prior.
  • This event occurred during the immediate postoperative period following inguinal hernia repair.
  • Platelet antiaggregant therapy was interrupted and replaced with flurbiprofen, following guidelines.

Findings:

  • The case highlights the possibility of late stent thrombosis in ordinary stents.
  • Interruption of antiplatelet therapy, even with alternative medications, may precede such events.
  • Late stent thrombosis can occur significantly after the initial stenting procedure.

Implications:

  • This case underscores the risks associated with interrupting antiplatelet therapy in coronary stent patients undergoing non-cardiac surgery.
  • It prompts a re-evaluation of management strategies for late stent thrombosis.
  • Further research is needed on optimal perioperative management of antiplatelet therapy in patients with coronary stents.

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