Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Wolbachia-host interactions: connecting phenotype to genotype.

Iñaki Iturbe-Ormaetxe1, Scott L O'Neill

  • 1School of Integrative Biology, The University of Queensland, St Lucia, QLD 4072, Brisbane, Australia.

Current Opinion in Microbiology
|June 1, 2007
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Long-Term Durability and Public Health Impact of City-Wide <i>w</i>Mel <i>Wolbachia</i> Mosquito Releases in Niterói, Brazil, During a Dengue Epidemic Surge.

Tropical medicine and infectious disease·2025
Same author

Correction: Large-scale releases and establishment of wMel Wolbachia in Aedes aegypti mosquitoes throughout the Cities of Bello, Medellín and Itagüí, Colombia.

PLoS neglected tropical diseases·2025
Same author

Successful introgression of wMel Wolbachia into Aedes aegypti populations in Fiji, Vanuatu and Kiribati.

PLoS neglected tropical diseases·2024
Same author

Large-scale releases and establishment of wMel Wolbachia in Aedes aegypti mosquitoes throughout the Cities of Bello, Medellín and Itagüí, Colombia.

PLoS neglected tropical diseases·2023
Same author

Reduced dengue incidence following city-wide wMel Wolbachia mosquito releases throughout three Colombian cities: Interrupted time series analysis and a prospective case-control study.

PLoS neglected tropical diseases·2023
Same author

Transient Introgression of <i>Wolbachia</i> into <i>Aedes aegypti</i> Populations Does Not Elicit an Antibody Response to <i>Wolbachia</i> Surface Protein in Community Members.

Pathogens (Basel, Switzerland)·2022
Same journal

A conceptual framework to dissect emergent functions in microbial communities.

Current opinion in microbiology·2026
Same journal

Differential signaling roles of the KinA-KinE sensor kinases in regulating Spo0A, the master regulator of Bacillus subtilis cell‑fate decisions.

Current opinion in microbiology·2026
Same journal

S-layers as natural building blocks for nanobiotechnology and synthetic biology.

Current opinion in microbiology·2026
Same journal

The role of the antimicrobial peptide nisin as a clean label food preservative.

Current opinion in microbiology·2026
Same journal

From coarse-grained metabolic rules to fine-grained control of microbial communities.

Current opinion in microbiology·2026
Same journal

Progress in engineered bacterial cancer therapies.

Current opinion in microbiology·2026
See all related articles

Wolbachia bacteria, once seen only as insect parasites, now show complex interactions influencing insect traits. Understanding these host-symbiont relationships requires new genetic tools for both organisms.

Area of Science:

  • Microbial genetics
  • Insect biology
  • Symbiotic interactions

Background:

  • Wolbachia are intracellular bacteria infecting many insect species.
  • Traditionally viewed as reproductive parasites, Wolbachia are increasingly recognized for diverse host effects.
  • Recent Wolbachia genome sequencing offers insights into host-symbiont molecular mechanisms.

Purpose of the Study:

  • To explore the molecular basis of Wolbachia-mediated phenotypic variability in insects.
  • To bridge the gap between genomic data and observed host phenotypes.

Main Methods:

  • Comparative genomic analysis of Wolbachia genomes.
  • Utilizing model host systems, such as Drosophila, for studying host-symbiont interactions.

Main Results:

Related Experiment Videos

  • Genomic studies have identified potential genes and pathways involved in Wolbachia-host interactions.
  • Significant progress has been made in understanding the genetic underpinnings of Wolbachia's influence.

Conclusions:

  • A richer understanding of Wolbachia's role beyond parasitism is emerging.
  • Linking specific Wolbachia genotypes to host phenotypes necessitates the development of genetic manipulation techniques for both bacteria and insects.