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Updated: Jul 14, 2026

Semi-automated Analysis of Mouse Skeletal Muscle Morphology and Fiber-type Composition
Published on: August 31, 2017
Immunohistochemical study of differences between the muscle fiber types in the pars peripheralis and marginalis
Kun Hwang1, Dae Joong Kim, Se Ho Hwang
1Department of Plastic Surgery, Inha University College of Medicine, Sinheung-dong, Jung-gu, Incheon, Korea. jokerhg@inha.ac.kr
Abstract:
The aim of this study was to evaluate the immunohistochemical differences between the muscular fiber types in the pars peripheralis and pars marginalis of human orbicularis oris muscle. Five upper lips of fresh human adult cadavers were used. Full thickness of the upper lip, 5 mm in width, was harvested vertically at a peak point of cupid's bow. Troponin I-SS and Troponin I-FS antibodies were used to determinate the slow and fast skeletal muscle fibers. The pars peripheralis is composed of slow fibers (22%) and fast fibers (73%). The pars marginalis is composed of slow fibers (30%) and fast fibers (66%). We assume that the pars peripheralis and pars marginalis should be repaired sortably because the muscle reaction and endurance are not the same.
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