Related Experiment Video
Updated: Jul 14, 2026
06:53
Modeling Primary Bone Tumors and Bone Metastasis with Solid Tumor Graft Implantation into Bone
Published on: September 9, 2020
Proximal femoral replacement for metastatic bone disease
Mark W Manoso1, Deborah A Frassica, E Steven A Lietman
1Department of Orthopedic Surgery The Johns Hopkins Hospital, Baltimore, Md, USA.
Orthopedics
|June 2, 2007
Summary
Proximal femoral replacement effectively manages metastatic bone disease, offering pain relief and functional recovery. This surgical option is valuable when simpler reconstructions are not feasible for patients with bone metastases.
Area of Science:
- Orthopedic Surgery
- Oncology
- Reconstructive Surgery
Background:
- Metastatic bone disease often necessitates complex surgical interventions.
- Pathologic fractures of the proximal femur present significant reconstructive challenges.
Purpose of the Study:
- To evaluate the outcomes of proximal femoral replacement in patients with metastatic disease.
- To assess pain relief, functional restoration, and complication rates.
Main Methods:
- Retrospective review of 13 patients (14 hips) who underwent proximal femoral replacement between 1994 and 2000.
- Patients had an average age of 62 years, with renal cell carcinoma being the most common diagnosis.
- Postoperative management included full weight bearing and abduction brace use for 3-4 months.
Main Results:
- Seven patients experienced pathologic fractures.
- No dislocations, infections, or reoperations were reported.
- Ten patients died within 0.5-3.5 years due to their underlying disease.
Conclusions:
- Proximal femoral replacement is a viable option for managing metastatic disease in the proximal femur.
- The procedure offers significant pain relief and functional restoration.
- It is particularly indicated when less invasive reconstructive methods are not suitable.
