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Updated: Jul 14, 2026

Amide Coupling Reaction for the Synthesis of Bispyridine-based Ligands and Their Complexation to Platinum as Dinuclear Anticancer Agents
Published on: May 28, 2014
Phenolate- and acetate (both mu(2)-1,1 and mu(2)-1,3 mode)-bridged face-shared trioctahedral linear Ni(II)(3),
Anuj Kumar Sharma1, Francesc Lloret, Rabindranath Mukherjee
1Department of Chemistry, Indian Institute of Technology Kanpur, Kanpur 208 016, India.
Abstract:
The complexes [(L)(2)Ni(II)(2)M(II)(mu(2)-1,3-OAc)(2)(mu(2)-1,1-OAc)(2)(S)(2)] x xMeOH [HL = N-methyl-N-(2-hydroxybenzyl)-2-aminoethyl-2-pyridine; M = Ni, S = MeOH, x = 6 (1); M = Mn, S = H(2)O, x = 0 (2); M = Co, S = MeOH, x = 6 (3)] have been synthesized. Crystal structures reveal that three octahedral MII ions form a linear array with two terminal moieties {(L)Ni(II)(mu(2)-1,3-OAc)(mu(2)-1,1-OAc)(MeOH/H(2)O)}(-) in a facial donor set and a central MII ion which is connected to the terminal ions via bridging phenolate and two types of bridging acetates. Magnetic measurements reveal that the Ni(II)(3) and Ni(II)(2)Co(II) centers are ferromagnetically and Ni(II)(2)Mn(II) center is antiferromagnetically coupled. An attempt has been made to rationalize the observed magneto-structural behavior.
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