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Excessive gingival bleeding in two patients with Glanzmann thrombasthenia
Hilal Uslu Toygar1, Esra Guzeldemir
1Department of Periodontology, Faculty of Dentistry, Baskent University, Ankara, Turkey. usluhilaladana@yahoo.com
Journal of Periodontology
|June 2, 2007
Summary
Glanzmann thrombasthenia (GT), a rare inherited platelet disorder, can cause severe gingival bleeding. Periodontal treatment is safe and effective for GT patients with proper management and oral hygiene.
Area of Science:
- Hematology
- Periodontology
- Genetics
Background:
- Glanzmann thrombasthenia (GT) is a rare inherited platelet function disorder caused by defects in the glycoprotein IIb/IIIa complex.
- GT is often diagnosed in early childhood and can manifest as severe gingival hemorrhage.
- Consanguinity is associated with GT, particularly in regions with high rates of intermarriage.
Observation:
- Two female patients with GT presented with excessive gingival bleeding requiring periodontal intervention.
- One patient received platelet transfusion and periodontal therapy, while the other had undiagnosed GT and experienced bleeding post-procedure.
- Both patients had regular dental visit history.
Findings:
- Periodontal treatment in the first patient resulted in successful healing without complications.
- The first patient maintained good oral hygiene and experienced no periodontal issues during a 2-year follow-up.
- The second patient did not attend follow-up appointments.
Implications:
- Gingival bleeding can be an early indicator of hematologic disorders, necessitating dental professional awareness.
- Collaboration between dentists and hematologists is crucial for managing patients with GT.
- Effective periodontal treatment and diligent oral hygiene can lead to favorable outcomes for GT patients.
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