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Correction of Presbyopia by Monocular Bi-Aspheric Ablation Profile

Published on: September 20, 2024

LASIK and dry eye.

¹Minamiaoyama Eye Clinic, Tokyo, Japan. ikuko@tka.att.ne.jp

Comprehensive Ophthalmology Update

|June 2, 2007

Summary

Dry eye is a common LASIK complication, potentially caused by corneal nerve damage affecting tear production. Treatments include artificial tears, cyclosporine, and serum eye drops.

Area of Science:

Ophthalmology
Corneal Surgery
Dry Eye Disease

Background:

Dry eye is a frequent complication following laser-assisted in situ keratomileusis (LASIK).
Clinical signs include ocular surface staining, reduced tear film stability, and decreased corneal sensitivity.
Symptoms and signs can persist for at least one month post-LASIK.

Purpose of the Study:

To explore the mechanisms behind post-LASIK dry eye.
To investigate the role of corneal innervation and other factors in dry eye development.
To review current and recommended treatments for post-LASIK dry eye.

Main Methods:

Review of clinical signs and symptoms associated with post-LASIK dry eye.
Analysis of potential mechanisms, including corneal innervation loss and its impact on tear secretion.

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Evaluation of treatment strategies for dry eye.

Main Results:

Flap creation in LASIK surgery can disrupt corneal nerves, potentially impairing tear secretion.
Less severe dry eye symptoms are observed in LASIK enhancements involving flap-lifting compared to primary surgery.
Effective treatments include artificial tears, topical cyclosporine, hot compresses, punctal plugs, and autologous serum eye drops.

Conclusions:

Corneal nerve damage is a significant factor in post-LASIK dry eye, affecting tear film homeostasis.
Factors beyond neurotrophic effects may contribute to dry eye after LASIK.
Preoperative management for severe dry eye patients should include punctal plugs and serum eye drops.