Related Experiment Video

Updated: Mar 31, 2026

Subcellular Fractionation of Primary Chronic Lymphocytic Leukemia Cells to Monitor Nuclear/Cytoplasmic Protein Trafficking
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Chronic lymphocytic leukemia: keeping cell death at bay

Klaus-Michael Debatin1

  • 1Department of Pediatrics and Adolescent Medicine, University of Ulm, Eythstrasse 24, 89075, Ulm. klaus-michael.debatin@uniklinik-ulm.de

Cell
|June 2, 2007
PubMed
Summary

The study found that decreased expression of the DAPK1 gene is linked to chronic lymphocytic leukemia (CLL). This downregulation occurs through genetic and epigenetic changes in both familial and sporadic forms of the disease.

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