An update on antimicrobial central venous catheters

T S J Elliott1

  • 1Department of Clinical Microbiology and Infection Control, University Hospital Birmingham NHS Foundation Trust, The Queen Elizabeth Hospital, Edgbaston, Birmingham, B15 2TH, UK. Tom.Elliott@uhb.nhs.uk

Insights

Antimicrobial central venous catheters employ diverse mechanisms to prevent infections. While their use is limited and infection prevention role is under investigation, they offer clear benefits in specific clinical scenarios.

Area of Science:

  • Medical Devices
  • Infectious Disease Prevention
  • Biomaterials

Background:

  • Central venous catheters are crucial for patient care but pose infection risks.
  • Antimicrobial central venous catheters (ACVCs) are designed to mitigate these risks.
  • The mechanisms and efficacy of ACVCs are areas of ongoing research.

Purpose of the Study:

  • To review the antimicrobial mechanisms employed by central venous catheters.
  • To define the current applications and limitations of ACVCs.
  • To assess the role of ACVCs in preventing catheter-related infections.

Main Methods:

  • Literature review of studies on antimicrobial catheter mechanisms.
  • Analysis of clinical data on ACVC usage and infection rates.
  • Evaluation of different antimicrobial agents and delivery systems.

Main Results:

  • ACVCs utilize various strategies, including impregnated agents and coatings.
  • Current usage of ACVCs is infrequent, with ongoing research into their infection prevention capabilities.
  • Specific clinical situations have been identified where ACVCs demonstrate clear utility.

Conclusions:

  • Antimicrobial central venous catheters offer a promising approach to reducing catheter-related infections.
  • Further research is needed to fully establish the role and optimize the use of ACVCs.
  • ACVCs have defined applications in high-risk patient populations or settings.

Related Concept Videos

Endocarditis IV: Nursing Management01:29

Endocarditis IV: Nursing Management

Infective endocarditis (IE) is a chronic infection of the heart's endocardium, primarily affecting the heart valves. A detailed nursing assessment for a patient with IE involves collecting subjective and objective data to ensure an accurate diagnosis and timely intervention.Subjective DataThe nurse gathers information about the patient's symptoms and complaints during the subjective assessment. Patients with infective endocarditis often report non-specific symptoms that can mimic other...
Parentral Nutrition: Centeral and Peripheral Parental Nutrition01:27

Parentral Nutrition: Centeral and Peripheral Parental Nutrition

Parenteral Nutrition (PN) delivers essential nutrients directly into the bloodstream, bypassing the digestive system. It is commonly used for individuals with severe digestive disorders or conditions that prevent normal nutrient absorption.
PN can be administered through two primary routes:
1. Central Parenteral Nutrition (CPN):
CPN involves delivering a high concentration of nutrients through a large vein. This is typically achieved using a Peripherally Inserted Central Catheter (PICC) or,...
Aneurysm IV: Nursing Management01:22

Aneurysm IV: Nursing Management

Vigilant monitoring for aneurysm rupture is essential for patients undergoing aortic surgery.Preoperative Nursing ManagementContinuously monitor the patient for manifestations of aneurysm rupture, such as pallor, weakness, tachycardia, hypotension, abdominal, back, groin, or periumbilical pain, changes in consciousness, and a pulsating abdominal mass. Regularly assess the patient's peripheral pulses.Instruct the patient to consume a clear liquid diet the day before surgery and administer...
Healthcare Associated Infections II: Preventive Measures01:22

Healthcare Associated Infections II: Preventive Measures

Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
Hand hygiene01:23

Hand hygiene

Asepsis is the practice of preventing or breaking the chain of infection. The nurse employs aseptic techniques to prevent the spread of microorganisms and reduce the risk of diseases. Hand hygiene is the cornerstone of aseptic techniques and is classified into medical and surgical asepsis. Medical asepsis includes hand hygiene and the use of gloves. Surgical asepsis, or the sterile technique, refers to practices that render and keep objects and areas free of microorganisms.
Hand washing...
Urinary Tract Infection IV: Nursing Management01:17

Urinary Tract Infection IV: Nursing Management

In managing urinary tract infections (UTIs) in nursing, a comprehensive assessment is essential. Begin by gathering subjective data, such as the patient’s complaints of dysuria (painful urination), urinary frequency, urgency, suprapubic pain, and any lower abdominal discomfort. This information can be complemented by questions regarding previous UTIs, sexual activity, and personal hygiene practices, which can provide insight into risk factors. Objective assessment should focus on signs like...