Nanoscale compositional mapping with gentle forces
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Updated: Jul 14, 2026

Modeling Ligands into Maps Derived from Electron Cryomicroscopy
Published on: July 19, 2024
Ricardo García1, Robert Magerle, Ruben Perez
1Instituto de Microelectrónica de Madrid, CSIC, 28760 Tres Cantos, Madrid, Spain. rgarcia@imm.cnm.csic.es
Abstract:
Microscopists have always pursued the development of an instrument that combines topography and materials properties analyses at the highest resolution. The measurement of the tiny amount of energy dissipated by a vibrating tip in the proximity of the sample surface has provided atomic force microscopes with a robust and versatile method to determine the morphology and the compositional variations of surfaces in their natural environment. Applications in biology, polymer science and microelectronics illustrate the potential of phase-imaging force microscopy for nanoscale analysis.
