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Molecular cloning and characterization of Rab6 gene in duck

Biao Dong1, Daoqing Gong, Zhiliang Gu

  • 1School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai, P. R. China.

DNA Sequence : the Journal of DNA Sequencing and Mapping
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Rab Proteins01:14

Rab Proteins

Rab proteins constitute the largest family of monomeric GTPases, of which 70 members are present in humans. Rab proteins and their effectors regulate consecutive stages of vesicle transport such as vesicle transport, docking, and fusion to the correct recipient membrane.
Rab proteins switch between a cytosolic, GDP-bound inactive state and a membrane-anchored, GTP-bound active state. By themselves, Rabs show slow rates of GDP/GTP exchange and GTP hydrolysis. Thus, Rab proteins are considered...