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Related Concept Videos

Allergic Reactions02:06

Allergic Reactions

Overview
Allergic Reactions: Anaphylaxis01:30

Allergic Reactions: Anaphylaxis

Anaphylaxis is a severe, life-threatening hypersensitivity reaction mediated by Immunoglobulin E (IgE) antibodies. When IgE binds to allergens, it triggers the release of mediators– histamine, leukotrienes, and prostaglandins from mast cells and basophils. These mediators cause vasodilation, edema, and inflammation, leading to various symptoms.The primary allergens causing anaphylaxis include food items (e.g., peanuts, shellfish), drugs (e.g., penicillin, asparaginase, corticotropin, heparin),...
Microbiome of the Eye01:22

Microbiome of the Eye

The human eye has a specialized microbiota that reflects its unique anatomical and immunological environment. This low-biomass microbial community predominantly colonizes the conjunctiva and eyelid margins, playing a vital role in ocular surface homeostasis and defense. Despite its proximity to the richly colonized facial skin, the ocular surface maintains a distinct microbial profile due to continuous mechanical and biochemical defense mechanisms.The conjunctival surface hosts fewer microbial...
Allergic Drug Reactions01:27

Allergic Drug Reactions

Allergic reactions related to drugs are hypersensitivity responses driven by the immune system and bear no connection to the drug's therapeutic action. While drugs in isolation do not trigger an immune response, they can interact with endogenous proteins to form antigens. These antigens stimulate lymphocytes to produce antibodies. IgE-type antibodies attach themselves to mast cells. Upon subsequent exposure to the same stimulus, the antigen-antibody interaction is initiated, unleashing numerous...
Drug Toxicity: Allergic Reactions01:30

Drug Toxicity: Allergic Reactions

Drug-related allergies are immune-mediated responses triggered by the administration of pharmacological agents. These hypersensitivity reactions are classified based on the immune mechanisms involved. The four primary types—Type I, II, III, and IV—are mediated by different immunological pathways and exhibit distinct clinical manifestations.Type I Hypersensitivity/ IgE-Mediated Reactions: Immunoglobulin E (IgE) immediately mediates Type I hypersensitivity reactions. Upon initial exposure to a...
Asthma I: Introduction01:28

Asthma I: Introduction

Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...

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Symptom's resolution and growth outcome of children with cow's milk protein allergy consuming two hydrolyzed formulas: A retrospective study in Mexico.

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Related Experiment Video

Updated: Jul 14, 2026

A Non-invasive Way to Isolate and Phenotype Cells from the Conjunctiva
07:35

A Non-invasive Way to Isolate and Phenotype Cells from the Conjunctiva

Published on: July 5, 2017

[Allergic conjunctivitis in children].

Benjamín Zepeda Ortega1, Miguel Angel Rosas Vargas, Fernando Mitsutoshi Ito Tsuchiya

  • 1Hospital Infantil de México Federico Gómez.

Revista Alergia Mexico (Tecamachalco, Puebla, Mexico : 1993)
|June 5, 2007
PubMed
Summary

Allergic conjunctivitis, common in children, involves ocular surface inflammation due to type 1 hypersensitivity. This review details its symptoms, classification, pathophysiology, and treatments for allergic eye disease.

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Last Updated: Jul 14, 2026

A Non-invasive Way to Isolate and Phenotype Cells from the Conjunctiva
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Published on: July 5, 2017

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Area of Science:

  • Ophthalmology
  • Allergology
  • Immunology

Context:

  • Allergic conjunctivitis encompasses diverse ocular surface diseases, frequently occurring in childhood.
  • It is intrinsically linked to type 1 hypersensitivity reactions and other allergic conditions.
  • The condition presents with acute (seasonal, perennial) and chronic (vernal, atopic, giant papillary) forms.

Purpose:

  • To offer a comprehensive overview of allergic conjunctivitis.
  • To elucidate the symptoms, classification, and physiopathology of this prevalent allergic disease.
  • To discuss recent advancements in the treatment of allergic conjunctivitis.

Summary:

  • Ocular surface inflammation in allergic conjunctivitis triggers symptoms like itching, tearing, edema, redness, and photophobia.
  • Chronic forms, particularly vernal keratoconjunctivitis, can lead to corneal lesions and visual impairment.
  • The late-phase response involves eosinophilia and neutrophilia, with potential for ocular surface tissue remodeling.

Impact:

  • Enhances understanding of allergic conjunctivitis for clinicians and researchers.
  • Provides a foundation for improved diagnostic and therapeutic strategies.
  • Contributes to better management of allergic eye disease, especially in pediatric populations.