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Multiple juvenile xanthogranulomas in a 13-year-old.

Kelley Pagliai Redbord¹, Anita P Sheth

¹Department of Dermatology, College of Medicine, University of Cincinnati, Cincinnati, Ohio, USA.

Pediatric Dermatology

|June 5, 2007

Summary

Multiple juvenile xanthogranuloma, a rare condition typically seen in infants, presented unusually in a 13-year-old girl. This case highlights the need for broader differential diagnoses in older children.

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Area of Science:

Dermatology
Pediatric Pathology

Background:

Juvenile xanthogranuloma (JXG) is a rare histiocytic disorder.
Typically presents in infancy, often with solitary cutaneous lesions.

Observation:

A 13-year-old girl presented with multiple asymptomatic, 3-6 mm, orange-yellow papules on her trunk and extremities.
Histopathology revealed dermal infiltrates with Touton-type giant cells, lymphocytes, and macrophages.

Findings:

The patient was diagnosed with multiple juvenile xanthogranuloma.
This presentation is uncommon, as JXG typically occurs in infants, and multiple lesions are rare in older children and adults.

Implications:

JXG should be considered in the differential diagnosis of cutaneous lesions in older children, not just infants.
Comprehensive work-up, including ophthalmology examination, is crucial for patients diagnosed with JXG.
Awareness among pediatricians and dermatologists is key for timely diagnosis and management.