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Multiple juvenile xanthogranulomas in a 13-year-old.
Kelley Pagliai Redbord1, Anita P Sheth
1Department of Dermatology, College of Medicine, University of Cincinnati, Cincinnati, Ohio, USA.
Pediatric Dermatology
|June 5, 2007
Summary
Multiple juvenile xanthogranuloma, a rare condition typically seen in infants, presented unusually in a 13-year-old girl. This case highlights the need for broader differential diagnoses in older children.
Area of Science:
- Dermatology
- Pediatric Pathology
Background:
- Juvenile xanthogranuloma (JXG) is a rare histiocytic disorder.
- Typically presents in infancy, often with solitary cutaneous lesions.
Observation:
- A 13-year-old girl presented with multiple asymptomatic, 3-6 mm, orange-yellow papules on her trunk and extremities.
- Histopathology revealed dermal infiltrates with Touton-type giant cells, lymphocytes, and macrophages.
Findings:
- The patient was diagnosed with multiple juvenile xanthogranuloma.
- This presentation is uncommon, as JXG typically occurs in infants, and multiple lesions are rare in older children and adults.
Implications:
- JXG should be considered in the differential diagnosis of cutaneous lesions in older children, not just infants.
- Comprehensive work-up, including ophthalmology examination, is crucial for patients diagnosed with JXG.
- Awareness among pediatricians and dermatologists is key for timely diagnosis and management.
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